Rocuronium (Br)

'Rocuronium (Br) is a non-depolarizing skeletal muscle rexalant. Rocuronium (Br) is used as an adjunct to anaesthesia. Rocuronium (Br) is a competitive neuromuscular blocking agent. It affects the transmission at the neuromuscualr junction. Rocuronium is an injectable, nondepolarizing neuromuscular blocking drug. It was developed out of a need for an agent with a rapid onset and short duration of action, and a low risk of side effects. Rocuronium''s onset of action is comparable to that of succinylcholine, but its duration of action is significantly longer. Compared with other nondepolarizing agents, rocuronium has a similar side effect profile but a more rapid onset of action. Rocuronium was approved by the FDA in March 1994.'

Brands

ESMERON ESMERON

Adult Dose

Dose: 0.15 mg/ kg
Single Dose: 0.15 (0.15)
Frequency: As recommended.
Route: IV
Instructions: Maintenance as required

Neonatal

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Paedriatic

Characteristics

belongs to Amino Steroid. It belongs to Muscle Relaxants pharmacological group.The Molecular Weight of Rocuronium (Br) is 609.70.

Contraindications

Rocuronium (Br)

Effects

The symptomatic adverse reactions produced by Rocuronium (Br) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Tachycardia, Rashes, Pruritus, Cardiac arrhythmias, Edema, Bronchospasm, Hypertension, Hiccups, Transient hypotension.

Indications

Rocuronium (Br) is primarily indicated in conditions like Adjunct to anesthesia, Muscle relaxation (intermediate duration) during intensive care, Muscle relaxation (intermediate duration) for surgery or intubation, Muscular spasm.

Interactions

Rocuronium (Br) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementClindamycinLignocaineLincomycin (HCl)Mivacurium (Cl)Polymyxin B (Sulphate)Procainamide (HCl)QuinidineVerapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interfrence

Risks

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Inj Store in refrigerator.

Warnings

Rocuronium should be used with caution in patients with impaired kidney or liver function.

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