Rabies Immune Globulin

Rabies Immune Globulin is a liquid or freeze dried preparation containing human globulins, mainly immunoglobulin G (IgG). Rabies Immune Globulin is obtained from plasma of donors immunised agianst rabies and contains specific antibodies that neutralise the rabies virus. Rabies Immune Globulin is used for passive immunization indicated for persons suspected of exposure to rabies specially in case of severe exposure.


Adult Dose
Dose: 20 IU/ kg
Single Dose: 20 (20)
Frequency: As recommended.
Route: IM
Instructions: Single dose. If possible part of the dose should be infiltered around the wound.
Neonatal
Paedriatic
Dose: 20 IU/kg
Single Dose: 20 (20)
Frequency: 24 hourly
Route: Intra Muscular
Instructions: When Required
Characteristics
. It is of Natural origin and belongs to Globulins. It belongs to Rabies Prophylaxis Products and Immune Globulin pharmacological group.It is weakly acidic drug.
Contraindications
Rabies Immune Globulin is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Rabies Immune Globulin, which give rise to further complications include Anaphylactoid reactions.The symptomatic adverse reactions produced by Rabies Immune Globulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Urticaria, Angioedema, Soreness, Muscle soreness, Stiffiness.
Indications
Rabies Immune Globulin is primarily indicated in conditions like Rabies prophylaxis.
Interactions
No data regarding the interactions of Rabies Immune Globulin was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IM Inj Store in refrigerator.
Warnings
Avoid IV administration of this preparation and give IM with caution in patient with thrombocytopenia and coagulopathies. Caution should be done in patients with hypersensitivity reactions to immune globulin or thimerosal.
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