Pyrilamine (Maleate)

Pyrilamine (Maleate) is anti-histamine, used in treatment of allergic rhinitis and allergic conjunctivitis and for prevention of allergic reactions to blood or plasma in patients with a known history of such reactions.


Adult Dose
Dose: 0.10%
Single Dose: 0.1 (0.1)
Frequency: 4 hourly
Route: Ophthalmic
Instructions: As required.
Neonatal
Paedriatic
Characteristics
belongs to Ethylenediamine. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action and also classified in Anti Allergic Agent pharmacological group.The Molecular Weight of Pyrilamine (Maleate) is 401.50. It is weakly acidic drug.
Contraindications
Pyrilamine (Maleate)
Effects
Pyrilamine (Maleate) produces potentially life-threatening effects which include Bone marrow suppression. which are responsible for the discontinuation of Pyrilamine (Maleate) therapy.The signs and symptoms that are produced after the acute overdosage of Pyrilamine (Maleate) include Convulsions, Coma, Unconsciousness, Hypertension.The symptomatic adverse reactions produced by Pyrilamine (Maleate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Paresthesias.
Indications
Pyrilamine (Maleate) is primarily indicated in conditions like Cold, Cough, Hypersensitivity reactions, Pruritus.
Interactions
No data regarding the interactions of Pyrilamine (Maleate) was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps, Susp, Liq Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Pyrilamine should be used with caution in bone marrow depression. Patients should observe caution while driving or performing other task requiring alertness because it may cause drowsiness. It should be used with caution in patients with urinary retention, history of bronchial asthma, hyperthyroidism, cardiovascular or liver disease. It should be used with caution in person with acute or chronic respiratory impairment, especially in children. Do not give S/C because irritation or lesion may occur.
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