Bisacodyl

'Bisacodyl is a stimulant laxative. Chemically Bisacodyl is identified as 4, 4''-(2-pyridylmethylene)diphenol diacetate. It acts by irritating the digestive tract and stimulates intestinal activity. Bisacodyl is effective in treating constipation or to clean out the intestinal tract before bowel examinations or bowel surgery.'

Brands
BISACODYL BICOLAX BICOLAX BISACODYL BISACODYL BISACODYL NOVOLUX NOVOLUX BISACODYL DECOLAX LAXIL LAXIL DULCOLAX DELAX BISACODYL BISACODYL BISCA BISACODYL BISACODYL BISACODYL
Adult Dose
Dose: 5 to 15 mg
Single Dose: 10 (10)
Frequency: 24 hourly
Route: PO
Instructions: At Bed Time
Neonatal
Dose: 0.312 mg/kg
Single Dose: 0.31 (0.312)
Frequency: 24 hourly
Route: oral
Instructions: At night
Paedriatic
Dose: 0.5 mg/kg
Single Dose: 0.5 (0.5)
Frequency: 24 hourly
Route: Intra Rectal
Instructions: -
Characteristics
. It is of Synthetic origin and belongs to Phenyl Pyridine. It belongs to Laxatives pharmacological group on the basis of mechanism of action and also classified in Stimulant pharmacological group.The Molecular Weight of Bisacodyl is 361.40.
Contraindications
Bisacodyl is contraindicated in conditions like Intestinal obstruction,Dehydration.
Effects
The severe or irreversible adverse effects of Bisacodyl, which give rise to further complications include Diarrhoea, Malabsorption, Protein-losing gastroenteropathy, Potassium depletion.The symptomatic adverse reactions produced by Bisacodyl are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Gastric irritation, Cramps.
Indications
Bisacodyl is primarily indicated in conditions like Bowel evacuation, Bowel preparation, Constipation, Prior to radiological procedures and surgery.
Interactions
No data regarding the interactions of Bisacodyl was found.
Interfrence
Falsely low readings for urinary glucose with Clintest and Diastix but not with Testape
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Suppositories, Enema Store Below 25°C. Tab Store in a well closed container, Below 40°C. Protect from Moisture.
Warnings
Bisacodyl should not be given to patients with intestinal obstruction or with undiagnosed abdominal symptoms. It should be used with care in patients with inflammatory bowl disease. Prolong use should be avoided. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because may cause allergic reactions (including bronchial asthma). Discontinue use if skin eruption occured.
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