Pinazepam

Pinazepam is a long-acting benzodiazepine, used in the short-term treatment of anxiety disorders and insomnia.


Brands
Adult Dose
Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 12 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Benzodiazepine. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in Sedatives and Hypnotics and Benzodiazepine pharmacological group.The Molecular Weight of Pinazepam is 308.80.
Contraindications
Pinazepam is contraindicated in conditions like Myasthenia gravis,Respiratory depression.
Effects
The symptomatic adverse reactions produced by Pinazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Headache, Drowsiness, Ataxia, Muscle weakness, Mild sedation.
Indications
Pinazepam is primarily indicated in conditions like Agitation, Anxiety, Depression, Irritability, Psychoneurosis, Tension.
Interactions
No data regarding the interactions of Pinazepam was found.
Interfrence
Risks
Drug should not be given to Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Perform periodic blood counts and liver function tests during long term therapy. Pinazepam should be used with caution in patients if increased salivation cause respiratory difficulty, because it may produce an increase in salivation. Give least amount of drug to patients in whom depression accompanies anxiety and suicidal tendencies may be present. It should be used with caution (if it contain tartrazine) in patients with aspirin hypersensitivity because it may cause allergic reaction (including bronchial asthma).
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