Oxybuprocaine

Oxybuprocaine most widely used topical local anesthetic which is used especially in opthalmolgy and otolaryngology. Oxybuprocaine (HCl) used as the hydrochloride in a 0.4% solution in short opthalmological procedures to produce surface anaesthesia of the eye.

Brands
ETHICAINE NOVESIN
Adult Dose
Dose: 0.40%
Single Dose: 0.4 (0.4)
Frequency: As recommended.
Route: Ophthalmic
Instructions: As required
Neonatal
Paedriatic
Dose: SA
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
belongs to Ester type. It belongs to Amine uptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Local Anesthetics pharmacological group.The Molecular Weight of Oxybuprocaine is 344.90. It is weakly acidic drug.
Contraindications
Oxybuprocaine is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Oxybuprocaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Hypotension, Agitation.
Indications
Oxybuprocaine is primarily indicated in conditions like Local anaesthesia for eye, Surface anaesthetic.
Interactions
No data regarding the interactions of Oxybuprocaine was found.
Interfrence
Risks
Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Eye Drops Store in a well closed container.
Warnings
Avoid Oxybuprocaine in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitated, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. It might be ototoxic and should not be instilled into the middle ear. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided.
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