Oxolinic Acid

Oxolinic Acid belongs to quinolone antibiotics. itsimilar in structure and function to nalidixic acid, used as an urinary antiseptic for treatment of urinary infections. May cause CNS stimulation and GI upset. Should not be given in epilepsy.

Brands
UTIBID
Adult Dose
Dose: 750 mg
Single Dose: 750 (750)
Frequency: 12 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Semi Synthetic origin. It belongs to DNA Gyrase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibacterial pharmacological group.
Contraindications
Oxolinic Acid is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Oxolinic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vomiting, Diarrhea, CNS effects.
Indications
Oxolinic Acid is primarily indicated in conditions like Cerebro-vascular insufficiency, Diabetic nephropathy, Peripheral vascular disease, Sickle cell disease.
Interactions
No data regarding the interactions of Oxolinic Acid was found.
Interfrence
Liver Function Test (LFT) Monitoring of hematologic profile
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Protect from Sunlight.
Warnings
Caution should be used in patients with renal insufficiency.Patients should be advised that quinolones may be associated with hypersensitivity reactions, even following a single dose, and to discontinue the drug at the first sign of a skin rash or other allergic reactions.
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