Nitrofurazone

Nitrofurazone is a local antibacterial agent, effective against a wide variety of gram positive and gram negative oragnisms. Nitrofurazone is used topically in the treatment of mixed, superficial infection of skin. Nitrofurazone is effective especially in the treatment of second and third degree burns and in skin grafting. Nitrofurazone is slowly acting drug and atleast 24 hours are required for it to take effect properly. Therefore, no treatment should be less than 2 or 3 days in duration.

Brands
FURACIN FURACIN FURAZOLINE NEUFRAZONE FURAZONE FURAZONE DOLDERCYN FURATOP FURATOP FURATOP FURACILLIN FURACILLIN GERMAX
Adult Dose
Dose: 0.20%
Single Dose: 0.2 (0.2)
Frequency: As recommended.
Route: Topical
Instructions: 2-4 times daily
Neonatal
Paedriatic
Dose: SA
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
Nitrofurazone also known as Nitrofural. . It is of Synthetic origin and belongs to Nitrofuran. It belongs to Dermatological Products and Antibiotic, Topical pharmacological group.The Molecular Weight of Nitrofurazone is 198.10.
Contraindications
Nitrofurazone is contraindicated in conditions like Renal impairment.
Effects
The severe or irreversible adverse effects of Nitrofurazone, which give rise to further complications include Peripheral neuropathy, Thromboembolic disorder.The symptomatic adverse reactions produced by Nitrofurazone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Vomiting, Dyspnea, Pain, Depression, Chest pain, Shortening of breath, Allergic skin reactions, Loss of vision, Calf pain, Numbness or weakness in extremity, Vision disturbances.
Indications
Nitrofurazone is primarily indicated in conditions like Bacterial infections, Bladder irrigation, Burns and ulcers, Dermatosis, Otitis media, Skin infections, Wounds.
Interactions
No data regarding the interactions of Nitrofurazone was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Cream, Oint, Topical Soln Store in a well closed container, at room temperature, Below 30°C. Protect from Sunlight.
Warnings
Because of the risk of haemolysis, nitrofurazone by mouth should be used with caution in patients with glucose-6-phosphate dehydrogenase deficiency. Avoid use topical nitrofurazone in patients with known hypersensitivity. Preparations containing macrogil should be used with caution in renal impairment.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.