Loxoprofen (Sodium)

Loxoprofen (Sodium) is NSAID (non-steroidal antinflammatory drug) and a prodrug of a propionic acid derivative. It has antinflammatory and antipyretic properties. Loxoprofen (Sodium) is optically active and marketed as racemic mixture. Loxoprofen (Sodium) is not available in any combination preparations. Loxoprofen (Sodium) is administered orally.

Brands
LOXONIN XONI-FAST LOXFEN QIZTA
Adult Dose
Dose: 60 to 120 mg
Single Dose: 90 (90)
Frequency: As recommended.
Route: PO
Instructions: As Required
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Propionic acid. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Loxoprofen (Sodium) is 304.30. Its pKa is 4.2.
Contraindications
Loxoprofen (Sodium) is contraindicated in conditions like Peptic ulcer,Hypersensitivity,Haematological disorders.
Effects
The severe or irreversible adverse effects of Loxoprofen (Sodium), which give rise to further complications include Anemia, Anemia, Eosinophilia, Hypersensitivity reactions, Anemia, Leukemia.The symptomatic adverse reactions produced by Loxoprofen (Sodium) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anorexia, Abdominal pain, Rashes, Urticaria, Indigestion, Itching, StomatitisX, Heart burn, Increased intracranial pressure.
Indications
Loxoprofen (Sodium) is primarily indicated in conditions like Cervical spondylosis, Lumbago, Osteoarthritis, Pain, Periarthritis, Rheumatoid arthritis, Toothache.
Interactions
No data regarding the interactions of Loxoprofen (Sodium) was found.
Interfrence
Increased Alkaline Phosphatase LevelsElevations of GOTand GPT
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab
Warnings
Loxoprofen may mask the usual sings and symptoms of injection. Therefore this drug should be used with an appropriate antibacterial agent for infections inflammation. Close observation and careful administration is also needed under this condition.
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