Lormetazepam

Lormetazepam is a short-acting benzodiazepine with general properties similar to those of diazepam. Lormetazepam is used as a hypnotic in the short-term management of insomnia.


Adult Dose
Dose: 0.5 to 1.5 mg
Single Dose: 1 (1)
Frequency: 24 hourly
Route: PO
Instructions: Once at bed time
Neonatal
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Benzodiazepine. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in Sedatives and Hypnotics pharmacological group.The Molecular Weight of Lormetazepam is 335.20.
Contraindications
Lormetazepam is contraindicated in conditions like Myasthenia gravis,Respiratory depression,Acute pulmonary insufficiency,Sleep apnea syndrome.
Effects
The symptomatic adverse reactions produced by Lormetazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Headache, Ataxia.
Indications
Lormetazepam is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.
Interactions
No data regarding the interactions of Lormetazepam was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store . Protect from Sunlight.
Warnings
Lormetazepam should be used with caution in patients with respiratory disease, muscle weakness, history of drug or alcohol abuse, marked personality disorder; avoid regular use during pregnancy (risk of neonatal withdrawl symptoms); use only if clear indication such as seizure control (high doses during late pregnancy or labour may cause neonatal hypothermia, hypotonia and respiratory depression); breast-feeding (present in milk, avoid if possible); reduce dose in elderly and debilitated, and in hepatic (avoid if severe) and renal impairment (start with small doses if severe); avoid prolong use (abrupt withdrawl thereafter); porphyria. It should not be used alone to treat depression (or anxiety associated with depression) or psychosis
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