Lodoxamide Tromethamine

Lodoxamide Tromethamine is antiallergic and used in the treatment of allergic conjunctivitis. Lodoxamide Tromethamine is a mast cell stabilizer with a similar profile of activity to Cromolyn Sodium. Lodoxamide Tromethamine is prepared by chemical synthesis and not present in any combination preprartions. Lodoxamide Tromethamine is available for opthalmic administration.


Adult Dose
Dose: 0.05 to 0.1 %
Single Dose: 0.075 (0.075)
Frequency: 6 hourly
Route: Ophthalmic
Instructions: -
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose: SA
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
. It is of Synthetic origin and belongs to Dioxamic Acid. It belongs to Opthalmic Products pharmacological group.The Molecular Weight of Lodoxamide Tromethamine is 553.90. Its pKa is 1.54.
Contraindications
Lodoxamide Tromethamine is contraindicated in conditions like Hypersensitivity.
Effects
The signs and symptoms that are produced after the acute overdosage of Lodoxamide Tromethamine include Diarrhea, Sweating, Light headedness, Warmth sensation, Stomach distension.The symptomatic adverse reactions produced by Lodoxamide Tromethamine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Burning, Flushing, Local irritation, Stinging on application, Blepharitis, Eye Pain, Corneal abrasion, Dry nose, Discomfort, Hyperemia, Dry eye, Excessive lacrimation, dizziness.
Indications
Lodoxamide Tromethamine is primarily indicated in conditions like Allergic perennial conjunctivitis, Atopic conjunctivitis, Keratosis, Vernal keratoconjunctivitis.
Interactions
No data regarding the interactions of Lodoxamide Tromethamine was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Eye Drops Store Below 40°C. Do not Freeze. Protect from Sunlight and Heat.
Warnings
Lodoxamide trimethamine should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with any illnesses or allergies. Avoid wearing soft contact lenses while using this because they may become damaged.
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