Eperisone (HCl)

'Chemically Eperisone (HCl) is identified as 4'' -ethyl-2-methyl-3-piperidinopropiophenone hydrochloride. It exihibits both skeletal muscle relaxant and vasodilator properties because of its actions within the central nervous stem and on vascular smooth muscles. Eperisone (HCl) is used in the symptomatic treatment of muscle spasm.'


Adult Dose
Dose: 50 mg
Single Dose: 50 (50)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Piperidinopropiophenone. It belongs to Anticholinergic Agent pharmacological group.The Molecular Weight of Eperisone (HCl) is 295.80. Its pKa is 9.6151.
Contraindications
Eperisone (HCl) is contraindicated in conditions like Hypersensitivity to the drug,Breast feeding.
Effects
The severe or irreversible adverse effects of Eperisone (HCl), which give rise to further complications include Hepatic and Renal rysfunction, Urinary disoeders.The symptomatic adverse reactions produced by Eperisone (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Weakness, Dizziness, Headache, Drowsiness, Diarrhea, Constipation, Insomnia, Abdominal pain, Skin rashes, Rashes, Itching, Nausea and vomiting, Numbness, Anemia, GI disturbance, Urinary retention, pruritis(less commonly), Skin rashes, dizziness.
Indications
Eperisone (HCl) is primarily indicated in conditions like Muscular spasm, Spasticity, and can also be given in adjunctive therapy as an alternative drug of choice in Musculoskeletal disorders.
Interactions
No data regarding the interactions of Eperisone (HCl) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store . Protect from Sunlight.
Warnings
It should be used with caution in patients with a history of hypersensitivity to any drug product and patient with hepatic function disorders.
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