Diphtheria, Tetanus and Pertussis Vaccine

Diphtheria, Tetanus and Pertussis Vaccine is a preparation of diphtheria formol toxoid and tetanus formol toxoid on a mineral carrier to which a suspension of killed Bordetella pertussis has been added. Diphtheria, Tetanus and Pertussis Vaccine is used for active immunization against diphthera, tetanus and pertussis in children from 2 months of age up to seven years of age. The mineral carrier may be hyderated aluminium phosphate or aluminiom hydroxide and the resulting mixture is approxmately iso tonic with blood, the antigenic properties are adversely afected certain actimicrobial preservaties those of phenotic type.

Brands
TRIVAC HB TETRACOQ PENTACT-HIB D.T.COQ GENETECH-DPT TRIVAC VACCINE
Adult Dose
Dose: IM
Single Dose: Usually given in children, refer Paediatric Dosage
Frequency:
Route:
Instructions:
Neonatal
Dose: 0.5 ml
Single Dose: 0.5 (0.5)
Frequency: As recommended.
Route: Intramuscular
Instructions: 3 doses at interval of 4 weeks,4th dose after 3---12 month
Paedriatic
Dose: 0.5 ml
Single Dose: 0.5 (0.5)
Frequency: As recommended.
Route: Intramuscular
Instructions: 3 doses at interval of 4 weeks. Booster dose at 1┬╜ years of age and then at 5 years of age.
Characteristics
Vaccinum diphtheria is the derivative of Diphtheria, Tetanus and Pertussis Vaccine. It is of Semi Synthetic origin. It belongs to Toxoids and Vaccines pharmacological group.
Contraindications
Diphtheria, Tetanus and Pertussis Vaccine is contraindicated in conditions like Infections,Fever.
Effects
The severe or irreversible adverse effects of Diphtheria, Tetanus and Pertussis Vaccine, which give rise to further complications include Convulsions.Diphtheria, Tetanus and Pertussis Vaccine produces potentially life-threatening effects which include Seizures, Encephalopathy. which are responsible for the discontinuation of Diphtheria, Tetanus and Pertussis Vaccine therapy.The symptomatic adverse reactions produced by Diphtheria, Tetanus and Pertussis Vaccine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Vomiting, Diarrhea, Fever, Restlessness, Pain, Redness, Collapse, Swelling at injection site.
Indications
Diphtheria, Tetanus and Pertussis Vaccine is primarily indicated in conditions like Dpt prevention.
Interactions
Diphtheria, Tetanus and Pertussis Vaccine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementPoliomyelitis VaccineIn the clinic or pharmacy, do not mix this vaccine with diphtheria, tetanus, pertussis (DTP) or DTaP in the same syringe as the strength of the polio vaccine may be decreased if prepared in this manner.Varicella Vaccine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store in refrigerator.
Warnings
Vaccine should be used with caution in patients with any illness, infection, blood disorder, seizure disorder or if have any allergy. This vaccine should not be administered to adults or to children 7 years of age or older. This vaccination should not be used in persons who have had a previous reaction to pertussis vaccine or who have recovered from pertussis illness.In fonts, with a personal or close family history of seizures precuations should be taken to avoid pyeria.
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