Diphtheria Antitoxin

Diphtheria Antitoxin is a sterile preparation containing the specific antitoxic globulins that have the power of neutralising the toxin formed by Corynebacterium diphtheriae. Diphtheria Antitoxin is used for passive immunization in suspected cases of diphtheria.


Adult Dose
Dose: 20000 to 120000 IU
Single Dose: 70000 (70000)
Frequency: As recommended.
Route: IM,IV Inf
Instructions: As Required
Neonatal
Dose: 10000 to 30000 IU
Single Dose: 20000 (20000)
Frequency: As recommended.
Route: Intra Muscular
Instructions: Once or as Required
Paedriatic
Dose: 10000 to 30000 IU
Single Dose: 20000 (20000)
Frequency: As recommended.
Route: Intra Muscular
Instructions: Once or as Required
Characteristics
belongs to Proteins. It belongs to Antitoxins and Antivenins pharmacological group.
Contraindications
Diphtheria Antitoxin is contraindicated in conditions like Asthma,Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Diphtheria Antitoxin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Fever, Itching, Muscle aching, Swelling of face, Swelling of feet.
Indications
Diphtheria Antitoxin is primarily indicated in conditions like Diphtheria.
Interactions
No data regarding the interactions of Diphtheria Antitoxin was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj, IM Inj Do not Freeze.
Warnings
Before injecting, information should be obtained whenever possible, as to whether previous injection have been received and whether the patient is subject to hypersensitivity disorders. Sensitivity testing should be performed before administration of antitoxin. The patient must be kept under observation after the administration of full dose. Adrenaline injection and resuscitation facilities should be available.It has a potency of not less than 1000 international units per ml when obtained from horse serum and not less than 500 international units /ml when obtained from otha mammals.
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