Diclofenac (K)

Diclofenac (K) is NSAID (non-steroidal anti-inflammatory drug). Diclofenac (K) is a simple phenylacetic acid derivative. It resembles both flurbiprofen and meclofenamate. It reduces fever and inflammation and relieves pain.


Brands
DICBRO SYDIP KEYGESIC KEYGESIC ARTONEC DOLO-K ARTIMOV-K ARTIMOV-K ARTIMOV-K DEFLAM DICFIN CATAFEN CATAFEN DOSIUM FRODIC-P NACTA POTAFIN ARTINIL-K ARTINIL-K ARTINIL-K DICLOVIS K OPAIN ZOFEN-K ZOFEN-K MAXIT MAXIT QUFEN-K QUFEN-K POTFENAC DENUM-K DENUM-K DENUM-K DENUM OPTEL-P DICK 50 DP-MED DP-MED ANTI-PAIN KLODIC HEUMATIC-K CAFLAM CAFLAM DICLODYN K TUZFEN OBNACK MOVOM P MOVOM P MOVOM P NEOFENIK NEOFENIK DICLO-P PAPLOFEN-P CLODIUM-K Phlodic K DICOWISE K DICLOWISE K RONSET RONSET DOLIJIT DOLGIT FENIK K DECTIL VOLTAFLAM VOLTAFLAM FASTAID PLUS DICLOFLAM-P DICLOREP OSTEFEN OSTEFEN DECLAM DECLAM RHEUMATIN-K RHEUMATIN-K MOVEN MOVEN MOVEN PANIK MOVAREN POTRAN POTRAN KOMFORT KLIC-F KLIC SWISO-P ANTIFLAM ANTIFLAM ANTIFLAM DICLOKALIUM CLONAP VALRON-P VALRON-P VALRON-P BIODIC-P AMDIK AMDIC DYNA-K MIFEN NEPNOP KANIC OSTI-P MACDAFIN DINOPEN CLOP DARDNIL ENGROL ARDI-K ARDI-K MUSKEL MUSKEL REGOPYRIN REGOPYRIN REGOPYRIN REGOPYRIN TONEK 75 GENEK-75 FLLASSIUM-K FENDIC VOLTEC-P VOLTEC-P VOLTEC-P LUXAFEN-K QUIKREL ZICLOPEL VACLO-POT VACLO-POT SIGNA SIGNA DICPOT RHEU-K RHEU-K ZAINEX ZAINEX KEMIPAN PLUS KEMIPAN RXOFLAM MOBIL-K DICLOMED COROMP KALFEN MOVE ORTHONIL-P FAPA DICLOWAN-QA MEDIFLAM BEFLAM DINAK UNIFIN MOUFLAM FEN-K HI-NIL DIC-P DIC-P DICLOSEL-P RELPAIN RELPAIN NAVEFLAM NAVEFLAM OLITASS DIPOLIVE SYFENAC SYFENAC DIKAN FLAMATROL RUMPO INFLABAN INFLABAN CAVERON CAVERON NOAFLAM NOAFLAM NOAFLAM DIFSOM-P PAINOGIN PAINOGIN RUBOR RUBOR FENBAR RELSEC RELSEC RELSEC SYNDIFEN KETAGESIC KETAGESIC NEWDIK DICLOYAN-P POFEN POFEN GLIF-K GLIF-K JFENAC-P Reuqin NIPGESIC KAFENAC LOPRAN-P ALFAKALIUM DIFENE DIFENE DIFENE ARIFLAM ARIFLAM ARIFLAM ALDAL ALDAL PHENPAL PHENPAL ANDIC-K POTANIC-P DELTAFLAM DETAFLAM FRENDIK-P CLO-TASIUM PAINNIL P DOLOCALM LOFEN MAKAID-K MAKAID-K FAREOP POTADIC DFINEP DFINEP KETAWIN DICLOX PLUS NIMATIC QRELIF HONDIC K CARAFENACP CARAFENACP PAINLESS PAINLESS ACHEX ACHEX DICSIUM EPLOPOT EPLOPOT DICLOTUS K DICLOTUS K DICLOTUS-K DICLOTUS-K DIF-K MOOV-K MOOV-K XYKLO XYKLO DICFEN-P KERWEL DI-POT RONAC SR RONAC ARTHOPOT DICLOBRON-K DICLOWAN-P MARINAC-P MARINAC-P VOLDEN FORT K DIKPEL DICOP-K FLEXURA FLEXURA DOLOWEL DOLOWEL DICLOSAF-P DICLOSAF-P DICLOSAF-P VOREN-K Avorek SYDASIC FRISKY KENAC KENAC NOSTIF-K BASOCAP DORBID
Adult Dose
Dose: 50 mg
Single Dose: 50 (50)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose: 0.166 to 0.666 mg/kg
Single Dose: 0.42 (0.416)
Frequency: 8 hourly
Route: Oral
Instructions:
Characteristics
. It is of Synthetic origin and belongs to Phenylacetic Acid. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Diclofenac (K) is 334.20.
Contraindications
Diclofenac (K) is contraindicated in conditions like GI ulceration,Hypersensitivity.
Effects
The symptomatic adverse reactions produced by Diclofenac (K) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Rashes, GI upset, Elevation of liver enzymes, GI hemorrhage, Vision disturbances, Erythema multiforme.
Indications
Diclofenac (K) is primarily indicated in conditions like Adnexitis, Dysmenorrhoea, Inflammation, Migraine, Post-operative pain, Post-traumatic pain, Rheumatoid arthritis.
Interactions
Diclofenac (K) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAescinChlorpheniramine (Maleate)It increases effects of chlotpheniramine. as it is is a CYP3A4 inhibitorCholestyramineColestipol (HCl)Cyclosporin AMisoprostolNitrendipineMay increase the levels/effects of nitrendipineSucralfateVORICONAZOLEVoriconazole may increase the serum concentration of diclofenac by decreasing its metabolism. Monitor for changes in therapeutic and adverse effects of diclofenac if voriconazole is initiated, discontinued or dose changed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj, Tab, Eye Drops Store at room temperature. Do not Freeze. Protect from Sunlight.
Warnings
Diclofenac potassium should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, asthma, hypertension and other conditions predisposing to fluid retention. It should be used with extra care in the presence of existing uncontrolled infection. Perform periodic auditory (hearing) function test during chronic therapy. Discontinue drug if skin reaction occurs.
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