Chymotrypsin

Chymotrypsin is a proteolytic enzyme. Chymotrypsin is secreted by the pancrease as the inactive pro-enzyme chymotripsinogen. Chymotrypsin is a serine endopeptidase that preferentially cleaves peptide bonds on the carboxyl side of amino acids with bulky hydrophobic residues, particularly tyrosine, tryptophan, phenylalanine and leucine. Chymotrypsin is effective in reducing soft tissue inflammtion especially associated with trauma.

Brands
CHYMORAL FORTE CHYMORAL MACTRYPSIN NOVOTRYPSIN CHYMOCIN WOBE-MUGOS E WOBE-MUGOS E WOBENZYM N CHYMOTRIP FORTE TRYPROL TRYPROL MEROSINE CHYMOMED ENZYLAN
Adult Dose
Dose: 100000 IU
Single Dose: 100000 (100000)
Frequency: 6 hourly
Route: PO
Instructions: Half hour before meal
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Proteolytic Enzyme. It belongs to Opthalmic Products pharmacological group.It is strongly acidic drug.
Contraindications
Chymotrypsin is contraindicated in conditions like Peptic ulcer,Renal diseases,Hepatic disease,Tuberculosis,Hypersensitivity to any component of product.
Effects
The symptomatic adverse reactions produced by Chymotrypsin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypersensitivity reactions, Corneal edema, Uveitis.
Indications
Chymotrypsin is primarily indicated in conditions like Edema, Inflammation, Oedema, Trauma.
Interactions
No data regarding the interactions of Chymotrypsin was found.
Interfrence
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Powder Store in a well closed container. Refrigeration is recommended. Protect from Sunlight and Moisture.
Warnings
The use of chymotrypsin is inadvisable in ocular surgery for patients under 20 years of age or patients with congenital character or high vitreous pressure.
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