Benzhexol (HCl)

Benzhexol (HCl) is anti-spasmodic drug. It relieves the abdominal pain and cramps. Benzhexol (HCl) is used in parkinsonism (mental disorder) of all cuases.Like atropine it also causes dry mouth , blurred vision, constipation, confusion and hallucinations. Salicylate of neostigmine is its effcetive antidote.

Brands

PACITANE HEXIDYL ZEXOL

Adult Dose

Dose: 1 to 2 mg daily
Single Dose: 1.5 (1.5)
Frequency: 24 hourly
Route: PO
Instructions: Trihexyphenidyl HCl in Idiopathic Parkinsonism:1mg is administered on first day and then increased by 2mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the post-encephalitic group, may require a total daily dose of 12 to 15 mg.

Neonatal

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Paedriatic

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Characteristics

Benzhexol (HCl) also known as Trihexyphenidyl. . It is of Synthetic origin and belongs to Piperidinepropanol. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group.The Molecular Weight of Benzhexol (HCl) is 337.90.

Contraindications

Benzhexol (HCl) is contraindicated in conditions like Narrow-angle glaucoma,Glaucoma,Hypersensitivity to the drug.

Effects

The severe or irreversible adverse effects of Benzhexol (HCl), which give rise to further complications include Tachycardia.The symptomatic adverse reactions produced by Benzhexol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Confusion, Hallucination, Euphoria, Agitation.

Indications

Benzhexol (HCl) is primarily indicated in conditions like Extrapyramidal disorders, Parkinsonism, and can also be given in adjunctive therapy as an alternative drug of choice in Advanced ovarian cancer.

Interactions

No data regarding the interactions of Benzhexol (HCl) was found.

Interfrence

Risks

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Elixir Store Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Tabs Store Below 40°C. Protect from Sunlight and Moisture.

Warnings

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