Cefoperazone

Cefoperazone is a third generation semisynthetic,β lactamase resistant cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a β lactam ring. Cefoperazone is a broad spectrum antibiotic effective against a large range of aerobic and anaerobic gram positive and gram negative bacteria. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cefoperazone (Na) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.


Brands
CEFBRO CEFBRO BENZONE BENZONE MAXONIL MAXONIL P-XONE P-XONE CEPRAZONE CEPRAZONE CEPRAZONE CEBAC CEBAC PERAZONE SULBAXON SULBAXON ELIZONE ELIZONE SALAR SALAR GRIZONE GRIZONE SUFZON SUFZON TOXIRID TOXIRID TOXIRID Q-BACT Q-BACT CEFAPEZONE SULKAM FORTE SULKAM FORTE PARABAC PARABAC L-BACTAM L-BACTAM PRONTOKEF PRONTOKEF BACTICEF BACTIMED BACTIMED BACTIMED PERASURE PERASURE CHEM ONE CHEM ONE BACTIZONE BACTIZONE BACTIZONE SULPAZONE D SEFOZONE SEFOZONE SEFOZONE SULPAZONE NEUTA NEUTA NEUTA NEUTA PAROAT PAROAT OBSAL OBSAL PERABID CEFOPEARL CEFOPEARL WISEBACT WISEBACT CEFOBID CEFOBID CEFOBID CEFOBID PHARSUL PHARSUL SOPRA INJECTION SOPRA INJECTION UNIBACTUM UNIBACTUM 2SUM 2SUM SAYZONE SAYZONE SAYZONE SAYZONE SULPRON SULPRON DARDUM DARDUM RAZOBACT RAZOBACT RAZOBACT GARNET GARNET GARNET DEEZONE DEEZONE DAISY 250 DAISY 500 DAISY 1000 DEACT DEACT ACTUM ACTUM ELEVA PLUS ELEVA PLUS ELEVA ELEVA ZIPAZOM ZIPAZOM ZIPAZOM SULCEFTA SULCEFTA HANPEZONE REXOPAR REXOPAR REXOPAR CEFBACTAM CEFBACTAM KAROZON PLUS KARAZON PLUS KAROZON KAROZON EFABEC EFABEC N PERAZONE N PERAZONE MIZIO EZONE EZONE MOKLIN FOBAC FOBAC CEFROZIL CEFROZIL KEPHAZON AZOSUL AZOSUL VALBACTUM VALBACTUM VALBACTUM SEBACTUM SEBACTUM NEOBACT NEOBACT PEBAC PEBAC PEBAC CERA CERA IMZONE IMZONE CEFOPLUS CEFOPLUS CEFACTUM CEFACTUM SULZEB SULZEB ADZONE ADZONE SULPERAZONE SULPERAZONE CEFRAZONE CEFRAZONE CEFRAZONE CEFOPAR CEFOPAR NENA-ZONE NENA-ZONE NENA-ZONE CEFOSUB SULZON SULZON PSULB PSULB ZAM EBACTUM SUZONE SUZONE CEFOID CEFOID CEFOID CEFOID MEGAROZE MEGAROZE USZONE USZONE CEFSUL CEFSUL CEFSUL FUTAZIM CEFODIUM CEFODIUM CEFODIUM RYTICEF PLUS RYTICEF PLUS OPI SAL OPI SAL FOPERA FOPERA QIN-BACT QIN-BACT JOOP JOOP SULCEF SULCEF ZONECEF ZONECEF ZONECEF CEBACTUM CEBACTUM ARICEF ARICEF ARICEF ZOPRAN ZOPRAN ZOPRAN BACTECEF BACTECEF SULBACEF PLUS SULBACEF PLUS C.P ZONE C.P ZONE C.P ZONE ERAZONE ERAZONE ERAZONE BIPED BIPED ZONESUL ZONESUL CEFPRAN CEFPRAN WINBACT WINBACT INJECTAZONE PLUS INJECTAZONE PLUS ZANTUM-1GM ZANTUM SACTUM SACTUM CEF-NA CEFPEC CEFPEC GREENEC GREENEC FENDER FENDER SULGEN SULGEN FORZON FORZON AIMPRAZONE AIMPRAZONE CEFRASUL CEFRASUL BACTUM BACTUM GILAXIM GILAXIM GILAXIM SULBRON SULBRON LINZONE LINZONE SUNBACT MECTRUM MECTRUM ZONDEX ZONDEX GILTUM GILTUM ASTELABECT ASTELABECT ARASALZONE ARASALZONE BRIXUL BRIXUL ZOBID LECFOBAC LECFOBAC MUTACEF MUTACEF NOVOCEF NOVOCEF AVESULZONE MONOBACT MONOBACT BEZONE BEZONE CEFEXTRA CEFEXTRA CEF + CEF +
Adult Dose
Dose: 1 to 2 g
Single Dose: 1.5 (1.5)
Frequency: 12 hourly
Route: IV/IM
Instructions:
Neonatal
Dose: 25 to 100 mg/kg
Single Dose: 62 (62.5)
Frequency: 12 hourly
Route: Intra Muscular
Instructions: -
Paedriatic
Dose: 25 to 100 mg/kg
Single Dose: 62 (62.5)
Frequency: 12 hourly
Route: Intra Muscular
Instructions: -
Characteristics
Cefoperazone (Na) is the derivative of Cefoperazone. It is of Semi Synthetic origin and belongs to Cephem Carboxylate. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin-3rd Gen pharmacological group.The Molecular Weight of Cefoperazone is 667.70.
Contraindications
Cefoperazone is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Cefoperazone, which give rise to further complications include Anemia, Gi bleeding, Hemolytic anemia, Leucopenia, Lymphocytosis, Bone marrow depression, Bleeding.The symptomatic adverse reactions produced by Cefoperazone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Anorexia, Fever, Dyspnea, Abdominal pain, Skin rashes, Chills, Urticaria, Paresthesias.
Indications
Cefoperazone is primarily indicated in conditions like Bone and joint infection, Pelvic inflammatory disease, Peritonitis, Respiratory tract infections, Septicaemia, Skin infections, Urinary tract infection.
Interactions
No data regarding the interactions of Cefoperazone was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Dry Powder for Inj Store Below 40°C. Protect from Sunlight.
Warnings
Cefoparazone should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.
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