Cefatrizine

Cefatrizine is a second generation semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a β lactam ring. Cefatrizine is used to treat a large variety of bacterial infections, such as respiratory tract, ear, skin and urinary tract infections. Cefatrizine is less effective against gram positive bacteria than first generation drugs. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cefatrizine is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.

Brands
ZANITRIN ZANITRIN ZANITRIN TIFOX TIFOX TIFOX FACTIVE FACTIVE FACTIVE FACTIVE AXEPIME AXEPIME
Adult Dose
Dose: 500 to 1000 mg
Single Dose: 750 (750)
Frequency: 12 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose: 10 to 20 mg/kg
Single Dose: 15 (15)
Frequency: 12 hourly
Route: Oral
Instructions: -
Characteristics
. It is of Semi Synthetic origin and belongs to Cephem Carboxylic Acid. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin pharmacological group.The Molecular Weight of Cefatrizine is 462.50.
Contraindications
Cefatrizine is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Cefatrizine, which give rise to further complications include Pseudomembranous colitis, Proteinuria, Hemolytic anemia, Bone marrow depression.The symptomatic adverse reactions produced by Cefatrizine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Anorexia, Diarrhea, Dyspnea, Abdominal pain, Skin rashes, Chills, Urticaria, Vaginitis, Candidiasis, Paresthesias, Bleeding.
Indications
Cefatrizine is primarily indicated in conditions like Bone and joint infection, Bronchitis, Otitis media, Pharyngitis, Pneumonia, Skin infections, Tonsillitis, Urinary tract infection.
Interactions
No data regarding the interactions of Cefatrizine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps, Susp Store in a well closed container, . Protect from Sunlight, Moisture and Heat.
Warnings
Cefatrizine should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.