Carbachol

Carbachol is a muscarinic and nicotinic agonist. It has a carbamic acid etser link which is not readily susceptible to hydrolysis by cholinesterases. It has all the pharmacologic properties of acetylcholine. Carbachol is used to reduce intraocular pressure in the treatment of glaucoma.

Brands
MIOSTAT MIOCHOL OCUSTAT OPHTH-CARB
Adult Dose
Dose: 0.01%
Single Dose: 0.01 (0.01)
Frequency: As recommended.
Route: Intra Occular
Instructions: As required
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Carbamoyl Choline. It belongs to Opthalmic Products and Antiglaucoma pharmacological group.The Molecular Weight of Carbachol is 182.60. It is weakly acidic drug, 2.82% solution of the drug is isotonic.
Contraindications
Carbachol is contraindicated in conditions like Inflammation,Iritis,Corneal abrasion.
Effects
The severe or irreversible adverse effects of Carbachol, which give rise to further complications include Hypotension, Bradycardia, Hypothermia, Profuse sweating, Explosive defecation.The symptomatic adverse reactions produced by Carbachol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, Blurred vision, Burning, Asthma, Stomachache, Eye Pain, Transient fall in BP, Decrease in visual acuity, Bullous keratopathy, Corneal clouding, Ciliary spasm, Intestinal cramps, Stinging.
Indications
Carbachol is primarily indicated in conditions like Glucoma, Miosis induction, Ocular hypertension.
Interactions
Carbachol is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementDiclofenac (Na)Homatropine (HBr) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Eye Drops Store Between 15°C-30°C. Protect from Sunlight and Heat.
Warnings
Carbachol should be used with caution in patients with eye problems, asthma, intestinal disease, ulcers, low or high blood pressure, heart disease, hyperthyroidism, seizures, Parkinsons disease or an obstruction of the urinary tract. Before having surgery with a general anesthetic, tell the doctor or dentist about the use of carbachol. Do not allow anyone else to use this medication. It is classified as pregnancy category C and should be used during pregnancy or lactation only if clearly needed.
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