Benzalkonium (Cl)

Benzalkonium (Cl) is a mixture of alkylbenzyl dimethylammonium chloride. Benzalkonium (Cl) is a rapidly acting surface disinfectant, antiseptic and detergent active against both gram negative and gram positive bacterias and certain viruses, fungi, yeasts and protozoa. Benzalkonium (Cl) is applied topically to the skin and mucous membranes. But recently Benzalkonium (Cl) is recommended that it should not be used as a antiseptic on skin because outbreak of infections have occurred due to bacterial growth.


Adult Dose
Dose: 0.01%
Single Dose: 0.01 (0.01)
Frequency: As recommended.
Route: Ophthalmic
Instructions: drops. As required.
Neonatal
Dose: 0.1 to 0.2 %
Single Dose: 0.15 (0.15)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Paedriatic
Dose: 0.1 to 0.2 %
Single Dose: 0.15 (0.15)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Characteristics
. It is of Synthetic origin and belongs to Benzylammonium salt. It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action. The Molecular Weight of Benzalkonium (Cl) is 339.50.
Contraindications
Benzalkonium (Cl) is contraindicated in conditions like Hypersensitivity.
Effects
The signs and symptoms that are produced after the acute overdosage of Benzalkonium (Cl) include Death, Vomiting, Convulsions, Coma, Collapse, Restlessness, Muscular weakness, Cyanosis, Dyspnea, Apprehension, Paralysis of respiratory muscle.The symptomatic adverse reactions produced by Benzalkonium (Cl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic contact dermatitis.
Indications
Benzalkonium (Cl) is primarily indicated in conditions like Bladder irrigation, Ear,eye,nose and throat irrigation, Gingivitis, Perodontal diseases, Preoperative disinfection of unbroken skin, Stomatitis, Thrush, Tonsillitis, Urethral irrigation, and can also be given in adjunctive therapy as an alternative drug of choice in Burns, Wounds.
Interactions
No data regarding the interactions of Benzalkonium (Cl) was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Topical Liq Store in a well closed container, Below 25°C.
Warnings
It is contraindicated during pregnancy in high doses causes high risk of birth defects also behavioral changes and skin changes.
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