Brinzolamide

Brinzolamide is used topically to reduce intra-ocular pressure in the management of glucoma and ocular hypertension.


Adult Dose
Dose: 0.5 mg
Single Dose: 0.5 (0.5)
Frequency: 8 hourly
Route: Ophthalmic
Instructions: Or 1% drops.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Sulphonamide. It belongs to Opthalmic Products and Antiglaucoma pharmacological group.The Molecular Weight of Brinzolamide is 383.50. It is weakly alkaline drug.
Contraindications
Brinzolamide is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Brinzolamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Blurred vision, Urticaria, Itching, Dermatitis, Rhinitis, Taste disturbances, Dryness of eye, Blepharitis, Eye discharge, Eye Pain.
Indications
Brinzolamide is primarily indicated in conditions like Glucoma, Ocular hypertension.
Interactions
No data regarding the interactions of Brinzolamide was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Eye Drops, Susp Store Below 40°C.
Warnings
Effects of prolonged use on corneal epithelial cells have not been evaluated; has not been studied in acute angle-closure glaucoma, renal impairment (parent and metabolite may accumulate). Patients with allergy to the sulfonamides; systemic absorption may cause serious reactions to recur. It is classified as pregnancy category C and should be used only when the benefit of therapy outweigh the risk to fetus.
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