Benzocaine

Benzocaine is a weak local anaesthetic similar to lignocain, used in proprietary preparations for sore throat. Benzocaine is insoluble ester type local anesthetic. It consist of an aromatic ring connected by an intermediate chain to an ionizable group, usually a tertiary amine. Applied topically to the skin and mucous membranes.

Brands
HITOGEN TYNO LOZENGES ORANGE TYNO LOZENGES ORANGE TYNO LOZENGES LEMON TYNO LOZENGES LEMON ARMADA ARMADA LISTERINE
Adult Dose
Dose: 1.5 to 3 mg
Single Dose: 2.2 (2.25)
Frequency: 8 hourly
Route: Ear
Instructions:
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose: 1.5 to 3 mg
Single Dose: 2.2 (2.25)
Frequency: 8 hourly
Route: Ear
Instructions: -
Characteristics
. It is of Synthetic origin and belongs to Ester type. It belongs to Dermatological Products and Local Anesthetics pharmacological group.The Molecular Weight of Benzocaine is 165.20.
Contraindications
Benzocaine is contraindicated in conditions like Bacterial infections,Opthalmologic anaesthesia.
Effects
The severe or irreversible adverse effects of Benzocaine, which give rise to further complications include Sinus tachycardia, Angioedema, Seizures, Methemoglobinemia, Sinus bradycardia.The symptomatic adverse reactions produced by Benzocaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Anxiety, Restlessness, Urticaria, Photosensitivity, Burning, Tremor, Edema, Contact dermatitis, Stinging on application, Urethritis, Tenderness.
Indications
Benzocaine is primarily indicated in conditions like Abrasion, Burns, Canker sores, Insect bites, Otitis externa, Otitis media, Pruritus, Rectal fissures, Rectal pain, Sore throat, Toothache.
Interactions
Benzocaine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementPrilocaine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Lozenges Store in a well closed container, at room temperature. Protect from Moisture. Skin Oint, Cream, Mouth Gel, Oint or Soln, Ear Soln, Aerosol Store at room temperature. Do not Freeze. Protect from Sunlight and Heat.
Warnings
Avoid continuous use for longer than 3 months. Avoid use in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitate, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. It might be ototoxic and should not be instilled into the middle ear. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided.
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