Azithromycin

The antimicrobial agents or antibiotics develops during the last 60 years are among the most dramatic examples of the advances of science. The remarkably powerful and specific activity of antimicrobial drug is due to their selectivity for highly specific targets that are either unique to micro-organism or much more important in them than in humans. Azithromycin belongs to a macrolide antibiotic. Azthromycin is a 15-atom lactone macrolide ring compound. Azithromycin is a semisynthetic derivative of Erythromycin obtained by the addition of methylated nitorgen into the lactone ring of Erythromycin. Azithromycin is effective against gram positive bacterias. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Azithromycin is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.


Brands
AZITHROCIN AZITHROCIN AZIBECT AZIBECT AZO AZO AZOXIN AZOXIN AZOXIN AZIROL AZOMAX AZOMAX AZOMAX AZOMAX AZROCIN AZROCIN ZITAMAX (ZITHROMAX) ZITAMAX (ZITHROMAX) PLAZO PLAZO AZIT AZIT REZOXIN RESQUE RESQUE MACRO-Z MACROBAC MACROBAC AZORES AZORES SPELL SPELL AZPAR AZPAR ZITHROFAME MEGATAB OD-3 OD-3 OD-3 ZEECIN ZEECIN ZEECIN ZEECIN AZOROX AZOROX AZIMYCIN AZIMYCIN AZIMYCIN AZOHEIM ZEZOT ZEZOT ZEZOT ZEZOT ZITHROMED ZITHROMED ZITHROMED ROMYCIN ROMYCIN BACTIZITH BACTIZITH BACTIZITH ZITHROSAN AZICIN AZICIN AZOCAM AZOCAM Z-MAC Z-MAC AZOCURE AZOCURE ROTHIN ROTHIN AZIOTIC AZIROMYCIN AZIROMYCIN ATHOFIX ATHOFIX EZONEX EZONEX EZONEX GEOZIT GEOZIT GEOZIT ZATROX ZORIX ZORIX AZICURE AZICURE AZICURE AZELIDE AZELIDE AZOUR AZOUR AZURE AZURE EZILL EZILL MACROMAX RASTHRO RASTHRO AZOLIVE MACROMYD ZOMYSIN RASMIC RASMIC RASMIC RASMIC RASMIC FORTE RASMIC FORTE AZIR BIOZIT ZEE ZEE AZIDOSE AZIDOSE MACROPORE RECLOCIN RECLOCIN RECLOCIN AZILITE AZILITE AZILITE ZIROCIN AZOLIB AZOLIB AZIROLIDE AZIROLIDE AZITHROCID AZITRAL AZIVID ZITH AZOMYCIN HAZID HAZID ZIROMAC EZIMAX ZIROMAX ZITON ENZOXEN EZMIN IRZAZITHO IRZAZITHO IRZAZITHO MEZOMED MEZOMED MYLIDE OTTOCIN OTTOCIN XABEST XABEST ZATROCIN ZATROCIN ZESTY ZETRO ZETRO ZETRO ZETRO ZICURE ZICURE ZOMAX ZOMAX ZOMAX ZOMAX ZYGREL ZYGREL ZYGREL AZIGOOD AZIMIC WINZITH WINZITH AZIWIN AZIMAL AZITEK TABLET AZIZEN AZOMEXIN AZOTAG AZROWIN AZROWIN AZROWIN DELIDE XIAXI THROB THROB THROB ZEPACK RAM-OFF RAM-OFF BIOZITH BIOZITH ZITHROVEL ZITHROVEL ZITHROVEL ZITHROVEL AZERA ZYCIN ZYCIN AZOTINE AZOTINE AZOTINE AZOTINE PRIZOCIN PRIZOCIN ZOTTER ZOTTER ZOTTER AZOWIN AZITHADVAN AZITHADVAN AZOMITE AZOMITE BLITZ AZIVER AZIVER AZITHRO AZITHRO AZOMER AZOMER AZOMER MYZITRO MYZITRO AZOCIN MAKSIN AZOGEN AZOGEN ZITHROWAN ZITHROWAN ATIZOR ATIZOR AZTRIX EXTHRO FENZY FENZY FENZY MYNEX MYNEX MYNEX AKZITH ARCIN AUSTA-Z AZI-ONCE CAPSULE AZIA AZITHROSAF AZITHROSAF AZITHROSAF AZITHROSAF AZITHSUN AZOFAS AZOGIL AZOGIL AZOGIL AZOM AZOM AZOMED AZOMED AZOPIK AZOPIK AZZA CARAMYCIN CARAROX CAROWN E-THRO E-THRO ERY-PACK ERY-PACK FAZI FAZI GRAZETH GRAZETH MACROCAP MACROZITH MACROZITH MAXIBEST MEDI-BIOTIC ROMY ROMY ROMY SILINA SYZCIN SYZCIN SYZCIN THRON ZEFED ZEFED ZEMARK ZEMARK ZITHROFAST ACASIA ACASIA ACRO ACRO ACRO ACRO ALIDE ALIDE ARTIWIN AZIROM AZIROM AZIZOX CHEMZEE AZIC AZI-ONCE TABLET KRAZE KRAZE MACZIN MACZIN ORZIT RAYAZ ZITHIN TABLET ZITHRAX AZIOMAK AZITA AZITEK SUSPENSION AZITHROMYCIN AZITHROMYCIN AZIX AZOROX CLOZIP D-KORTES KINRA MEGAZITH MEGAZITH MYZI NIMOCONIL RAMOFF WAZOCIN ZITHIN SUSPENSION ZITHRO ZITOCIN ZONACIN ZYSON SUSPENSION ZITHROSAFE ZEEROX WELROMYCIN LEGZITH AXALINA AZISIA AZOTEK AZOTEK EXONEX ZIM ZIM SERVAZ SERVAZ SERVAZ ZITREX ZITREX AZOBIT AZOMIN CINZIT HITH HYZITEK HYZITEK HYZITEK AZITAB AZITAB CONBAC HYZITH MEZITH SIMZITH ZEWIN ZEWIN ZITHOSIM ZITRO
Adult Dose
Dose: 250 to 2000 mg
Single Dose: 1100 (1125)
Frequency: 24 hourly
Route: PO
Instructions: Dose and duration may vary according to indication.
Neonatal
Dose: 6.25 to 12.5 mg/kg
Single Dose: 9.4 (9.375)
Frequency: As recommended.
Route: oral
Instructions: As required
Paedriatic
Dose: 20 mg/kg
Single Dose: 20 (20)
Frequency: As recommended.
Route: Oral
Instructions: As Required
Characteristics
. It is of Semi Synthetic origin and belongs to Azalide. It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Azithromycin is 785.00.
Contraindications
Azithromycin is contraindicated in conditions like Hypersensitivity,Hepatic impairment.
Effects
The severe or irreversible adverse effects of Azithromycin, which give rise to further complications include Pseudomembranous colitis, Jaundice, Maculopapular rash, Cholestasis.Azithromycin produces potentially life-threatening effects which include Anaphylaxis, Angioneurotic edema. which are responsible for the discontinuation of Azithromycin therapy.The signs and symptoms that are produced after the acute overdosage of Azithromycin include Severe vomiting, Severe diarrhea, severe nausea, Hearing loss.The symptomatic adverse reactions produced by Azithromycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Headache, Fatigue, Nausea, Vomiting, Diarrhea, Palpitation, Abdominal pain, Rashes, Photosensitivity, Deafness, GI disturbance.
Indications
Azithromycin is primarily indicated in conditions like Cervicitits, Lower respiratory tract infections, Multiple myeloma, Otitis media, Reversal of excessive bradycardia, Rtis; otitis media, Skin and soft tissue infections, Soft tissue and skin infections, Status epilepticus (unlicensed use), Upper respiratory tract infections, Urethritis.
Interactions
No data regarding the interactions of Azithromycin was found.
Interfrence
False elevated serum aspartate
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps, Oral Susp Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Azithromycin should be used with caution in patients with illness or any allergy, especially allergies to drugs, liver disease, jaundice, history of colitis or stomach problems or kidney disease.This drug should be used only if clearly needed during pregnancy or lactation.
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