Anastrazole

Anastrozole is antineoplastic agent, also called as anticancerous drug. Anastrozole is a new selective non-steroidal inhibitor of aromatase. Anastrozole is effective in the treatment of post-menopausal breast cancer in women to slow or stop the growth of abnormal cells, which is not responsive to tamoxifen.


Adult Dose
Dose: 1 to 10 mg
Single Dose: 5.5 (5.5)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
Anastrazole also known as Anastrozole. . It is of Synthetic origin and belongs to Methylpropiononitrile. It belongs to Chemotherapeutic Regimens and Antineoplastic Agent pharmacological group.The Molecular Weight of Anastrazole is 293.40.
Contraindications
Anastrazole
Effects
The severe or irreversible adverse effects of Anastrazole, which give rise to further complications include Thrombophlebitis, Leucopenia.The symptomatic adverse reactions produced by Anastrazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Anorexia, Diarrhea, Rashes, Asthenia, Arthralgia, Vaginal dryness, Hair thinning.
Indications
Anastrazole is primarily indicated in conditions like Breast cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Advanced breast cancer in postmenopausal women.
Interactions
No data regarding the interactions of Anastrazole was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Moisture and Heat.
Warnings
Anastrozole should be used with caution in patients with any illness (especially liver diseases) or any allergy. It is classified as pregnancy category D. Use of this medication is not recommended during pregnancy or lactation and in premenopausal womens. This medication is not recommended for use in children.
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