Almitrine

Almitrine is used as a respiratory stimulant in acute respiratory failure such as chronic obstructive pulmonary disease.


Brands
Adult Dose
Dose: 3 mg/kg
Single Dose: 3 (3)
Frequency: As recommended.
Route: IV Inf
Instructions: For 2 hours, in 2-3 div.doses.
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Methanesulfonate. It belongs to Vasotherapeutics pharmacological group.The Molecular Weight of Almitrine is 669.80. Its pKa is 4, 5.
Contraindications
Almitrine is contraindicated in conditions like Hepatic failure,Restrictive lung disease,Primary heart disease.
Effects
The severe or irreversible adverse effects of Almitrine, which give rise to further complications include Peripheral neuropathy.The signs and symptoms that are produced after the acute overdosage of Almitrine include Hyperventilation, Hypocapnia.The symptomatic adverse reactions produced by Almitrine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Drowsiness, Irritability, Nausea, Anxiety, Dyspnea, Palpitation, Insomnia, Weight LossX, Burning, Epigastric pain, Increased intracranial pressure, GI disturbance, Heaviness.
Indications
Almitrine is primarily indicated in conditions like Acute exacerbation of hypoxic coadaptation, Chronic respiratory failure in hypoxic load, Respiratory depression after anesthesia, Respiratory depression after drug overdose.
Interactions
No data regarding the interactions of Almitrine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Vial
Warnings
Almitrine should be used with caution in patient with hepatic disease. The best mean of achieving and maintaining therapeutic levels without toxic accumulation is by intrmittent dosing, this avoid the accumulation of drug on continuous dosing.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.