Dose: 0.17 mg/kg
Single Dose: 0.17 (0.17)
Frequency: 24 hourly
Route: PO
Instructions: -

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Synthetic origin and belongs to Cyclopyrolones. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group.The Molecular Weight of Zopiclone is 388.80. Its pKa is 6.7.

Zopiclone is contraindicated in conditions like Respiratory insufficiency.

The signs and symptoms that are produced after the acute overdosage of Zopiclone include Drowsiness, Ataxia, Lethargy.The symptomatic adverse reactions produced by Zopiclone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Confusion, Depressive moods.

Zopiclone is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.

Zopiclone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAtropine (Sulphate)CarbamazepineErythromycinMetoclopramide (HCl)Phenytoin (Na)RifampicinVORICONAZOLEVoriconazole may increase the serum concentration of zopiclone by decreasing its metabolism. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Paediatrics, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Perform periodic blood counts and liver function tests during long term therapy. Zopiclone should be used with caution in patients if increased salivation cause respiratory difficulty, because it may produce an increase in salivation. Give least amount of drug to patients in whom depression accompanies anxiety and suicidal tendencies may be present. It should be used with caution (if it contains tartrazine) in patients with aspirin hypersensitivity because it may cause allergic reaction (including bronchial asthma). Avoid use in patients with severe hepatic (liver) insufficiency.