Vitamin K

'Vitamin K is a fat soluble substance. Chemically Vitamin K is 2-methyl-1, 4-napthoquinone. It plays an important role in blood clotting, Vitamin K is essential cofactor in the hepatic synthesis of prothrombin and other blood clotting factors. Vitamin K is used in the treatment and prevention of hemorrhages and spontaneous bleeding associated with vitamin K deficiency or caused by some anticoaggulants (e.g coumarin). The dietary requirement of vitamin K is low because the vitamin is additionally synthesized by the bacteria that colonize the human intestine. Two natural forms of vitamin K exist: Vitamin K1, also called as phytonadione is found in many foods especially leafy green vegetables such as cabbage and spinach and also present in liver, cow''s milk, egg yolk and some cereals; Viatmin K 2, also known as menaquinone is synthesized by intestinal bacteria.'

Brands
K-VIT QUANTUM SUPER QUANTUM GOLD CLORAMIDINA COMPLEX VISIONACE
Adult Dose
Dose: 2.5 to 20 mg
Single Dose: 11 (11.25)
Frequency: As recommended.
Route: IV,IM,SC
Instructions: As required
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Naphthoquinone. It belongs to Nutrients and Vitamins pharmacological group on the basis of mechanism of action and also classified in Coagulant pharmacological group.The Molecular Weight of Vitamin K is 450.70. Its pKa is not ionizable.
Contraindications
Vitamin K
Effects
The severe or irreversible adverse effects of Vitamin K, which give rise to further complications include Bronchospasm, Sweating, Flushing, Hematoma, Chest tightness.Vitamin K produces potentially life-threatening effects which include Anaphylactic reactions. which are responsible for the discontinuation of Vitamin K therapy.
Indications
Vitamin K is primarily indicated in conditions like Haemorrhage, Over dosage of anticoagulants, Vitamin deficiency.
Interactions
Vitamin K is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCholestyramineColestipol (HCl)NicoumaloneOxytetracycline (Dihydrate)PhenindionePhenobarbitonePhenytoin (Na)Tocopherol (Vitamin E)Warfarin (Na)Vitamin K antagonize the hypoprothrombinemic effect of warfarinModerateIntake of vitamin K through supplement or diet should not chage during warfarin therapy. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 40°C. Protect from Sunlight and Heat.
Warnings
Vitamin K should be used with caution in patients with any pre-existing blood disorder or allergy. It should be used as directed during pregnancy or lactation.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.