VINJEC VINJEC Maparax VANCOCIN VANBACT VANBACT Vancotic Vancotic LYPHOCIN HISUN HISUN VAREDET VAREDET VANCOMYCIN VANCOMYCIN VANCORIN VANCORIN VANCORIN VANCORIN ZENGAC ZENGAC ZENGAC ZENGAC VANCOLON VANCOLON

Dose: 500 mg/ml of water
Single Dose: 500 (500)
Frequency: 6 hourly
Route: IV Inf
Instructions: Dose should be administered at no more than 10 mg/min or over a period of 1 hour.

Dose: 0.25 mg/kg.min
Single Dose: 0.25 (0.25)
Frequency: 8 hourly
Route: IV Infusion
Instructions: For 60 Minutes

Dose: 0.25 mg/kg.min
Single Dose: 0.25 (0.25)
Frequency: 8 hourly
Route: IV Infusion
Instructions: For 60 Minutes

. It is of Semi Synthetic origin and belongs to Glycopeptide. It belongs to Peptidoglycan transpeptidase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Vancomycin (HCl) is 1484.50.

Vancomycin (HCl)

Vancomycin (HCl) produces potentially life-threatening effects which include Nephrotoxicity, Renal damage, Uremia, Hematuria, Proteinuria. which are responsible for the discontinuation of Vancomycin (HCl) therapy.The symptomatic adverse reactions produced by Vancomycin (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Redness, Hypotension, Flushing, Urticarial skin rash, Eosinophilia, Red Man syndrome.

Vancomycin (HCl) is primarily indicated in conditions like Acute leukemia, Bacteremia, Brain abscesses, Chronic myeloid leukaemia, Colitis, Constipation and bowel evacuation, Endocarditis, Endocarditis prophylaxis, Endocarditis treatment, Meningitis, Peritonitis, Persistant neutropenia in advanced hiv infection, Prior to radiological procedures and surgery.

Vancomycin (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdefovir DipivoxilAmikacin (Sulphate)Amphotericin BBoth drugs produce nephrotoxic and neurotoxic effects results in increased adverse effects.ModerateClosely monitor for serum drug concentration, renal function andauditory and vestiular function.Cyclosporin AGentamicinMetformin (HCl)Vancomycin reduces the excretion of metformin by competing renal tubular transport results in increased level of metformin may lead to lactic acidosis.ModerateSlowly reduce the dose of metformin. Closely monitor the blood glucose level. Patient should notify to physician if experience signs of lactic acidosis.Netilmicin (Sulphate)OxaliplatinYou should inform your doctor before using this combination.Do not start or stop any medicine without doctor or pharmacist approval.StreptomycinConcurrent use may cause toxicities to the kidneys.Tobramycin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store Below 40°C.

Monitor blood pressure throughout infusion. Perform test for auditory (hearing) function and serum levels in patients with borderline kidney function and over the age of 60.Take appropriate measure in case of super infections (secondary infections).