Tienilic Acid

Tienilic Acid is a diuretic. It was formerly used in the treatment of edema and hypertension, but it has been withdrawn from the market due to severe side effects.

Brands

Adult Dose

Dose: 3.57 to 7.14 mg/kg
Single Dose: 5.4 (5.355)
Frequency: 24 hourly
Route: PO
Instructions: For atleast 6-Months

Neonatal

Paedriatic

Characteristics

. It is of Synthetic origin and belongs to Acetic Acid. It belongs to Renal tubular anion resorption inhibitor pharmacological group on the basis of mechanism of action and also classified in Diuretics pharmacological group.The Molecular Weight of Tienilic Acid is 331.20. Its pKa is 2.7.

Contraindications

Tienilic Acid is contraindicated in conditions like Thrombosis,Liver diseases,Renal calculi.

Effects

The severe or irreversible adverse effects of Tienilic Acid, which give rise to further complications include Hypokalemia, Dermatitis, Arthralgia.Tienilic Acid produces potentially life-threatening effects which include Renal failure, Hepatotoxicity. which are responsible for the discontinuation of Tienilic Acid therapy.

Indications

Tienilic Acid is primarily indicated in conditions like Hypertension, Infertility without hyperprolactinaemia.

Interactions

No data regarding the interactions of Tienilic Acid was found.

Interfrence

Risks

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Warnings

No data regarding the Warnings/Precuations of Tienilic Acid is available.

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