Thiamine HCl (Vitamin B1)

'Thiamine HCl (Vitamin B1) is a heat labile, water soluble bicyclic compound. Thiamine HCl (Vitamin B1) is made up of a substituted pyramidine ring connected by a methylene bridge to the nitrogen of a substituted thiazole ring. Thiamine HCl (Vitamin B1) is involved in carbohydrate metabolism in the body. it''s supplements are required to treat or prevent stomach, heart or nerve problems caused by inappropriate amount of thiamine. Thiamine deficiency can occur as a result of malnutrition or in conditions requiring increased need, such as pregnancy or illness. Thiamine HCl (Vitamin B1) is widely distributed in food, found in all plants and synthesized by some microrganisms, perticularly yeast. Cereals, nuts, peas, beans, liver, heart or kidney and fish are rich sources of thiamine.'


Brands
BECEFOL BECEFOL BECEFOL BEJECTAL BEJECTAL BEJECTAL-T BEJECTAL-T BEVIDOX BEVIDOX BEVIDOX DAYALETS IBERET FOLIC-500 GRADUMET IBERET FOLIC-500 GRADUMET IBERET-500 IBERET-500 IBEROL-F OPTILETS-M PRAMET-FA PRAMET-FA SURBEX SURBEX SURBEX-T SURBEX-T SURBEX-T SURBEX-Z SURBEX-Z TRIVIDOX VI-DAYLIN VI-DAYLIN VI-DAYLIN PERFECTIL VISIONACE NEUROTOL MULTIVITAMIN VIVIOPTAL ALVIT-B PIZOFEN-V PIZOFEN-V ANGLOPLEX ANGLOVIT ATCOPLEX -C ESSENTIALE CAP VITAMIN B COMPOUND VITAMIN B COMPOUND VITAMIN B COMPOUND THERAGRAN-H THERAGRAN-M THERAGRAN-NV THERAGRAN-NV THERAGRAN STRESS VITA BROOKES PLUS CAMOPLEX SUPER CAMOVIT-L CAMOVIT-L CAMOVIT-M CAMOZYME HEPTOCAM HEPTOCAM HEPTOCAM MENDOZA PLEX RONUVIT THIAVIT THIAVIT VITACAL XTRA DILCONEURINE DILCONEURINE DILCONEURINE DILCOZYME DILCOZYME DILCOZYME HEPALEX HEPALEX MINAMINO MINAMINO ONCE A DAY NERVIGOR NERVIGOR SIRON PEMINAL-500 PEMINAL-500 NEURO-S CYNODOX-C FORTE CYNODOX-C LYSINE CYNODOX-SF EPLAZYME EPLAZYME BCOPLEX BCOPLEX BCOPLEX B-COMPOUND FORTE ETHIBEX -T FORTE ETHIPLEX LIVOTONE OCULUVIT EXTRA BECODON-L MULTICAP-M ORACAP-T NURAMINE FORTE NURAMINE FORTE NURAMINE FORTE NURAMINE FORTE NURAMINE FORTE NURAMINE FORTE CYTAMEN COMPOUND CYTEXIN UNIPLEX WELLCOSINE FEFOL VIT SPANSULE FESOVIT-Z FESOVIT-Z REVITALE M REVITALE M REVITALE-B REVITALE-B STARVIT GROTAL PANVITAN-M VITRONEX ZYMOPLEX ZYMOPLEX LYSOBEX LYSOBEX LYSOBEX LYVIT TRIOVIT TRIOVIT TRIOVIT TRIOVIT UNIHAEM UNIHAEM VITANOL VITANOL VITANOL MULTINA-33 MULTINA-33 MULTINA-33 TRES-ORIX FORTE ENERVIT ENERVIT ENERVIT HICAP-M HICAP-SS PREGNOVIT NEUROSTRESS NEUROSTRESS NEUROSTRESS NEUROSTRESS-C NEUROSTRESS-L HEMOTON-S HEMOTON-S HEMOVIT VITROBION KAYCIPLEX-L PEXOVIT PEXOVIT PEXOVIT BINIPLEX BINIPLEX NOVOBION RUBEX VITCOM COMBIPLEX LYSOPLEX LYSOPLEX LYSOPLEX LEAMAX-C SOVIT-M TINCHU VIT MARVIPLEX MARVIPLEX VITAVIT VITAVIT VITAVIT VITAVIT CURACAP-T ENZOVIT UNIVIT UNIVIT-M MIOBI DOLO-NEUROBION MULTIBIONTA MULTIBIONTA MULTIBIONTA MULTIBIONTA-M MULTIBIONTA-M NEUROBION NEUROBION POLYBION FORTE POLYBION FORTE SANGOBION BIOLYSINE MULTICAL-PLUS HANYBEC MULTINAF NEUROBEC MOSEGOR-V MOSEGOR-V SANTEVINI PLUS OPALEX -L POLYZYMA NURO-VIT OROPLEX OROPLEX OROPLEX-C FORTE VITAFER OSSO PLUS VITALET-H VITALET-M ABDEC ABDEC FERRODIN FERRODIN-F POLYVIT POLYVIT-M VIBION VITAMIN B COMPOUND LYSOVIT UNICAP UNICAP-M UNICAP-T ALDALYSINE ALDALYSINE ALDAPLEX ARUNAPLEX ARUNAPLEX CESTONIL PLUS CESTONIL PLUS REKOPLEX FORTE REVITON REVITON BECOZYM FORTE BENERVA BEROCCA LITRISON SUPRADYN-N TRIMETABOL MEGAVIT MEGAVIT ENRICH GLYVISOL VIOPHOS-B DIGEPLEX GENATOSAN DYNAMIN-NV DYNAMIN-V SANJUIS FERVIT FERVIT VASEDEX-C DIADYNAM-G VITAGLOBIN CALIX UNESKOBIAN UNESKOBIAN UNESKO-T UNESKO-T BC-LYSE TREOBION AWARDIN HIGH-C PLUS NUTRITION-12 NUTRITION-6 NEUROVIT NEUROVIT AQUA VIT CALCEE PLUS VITALEX GROVIT GROVIT CENTRUM INCREMIN LEDERPLEX MATERNA STRESSTABS VI-MAGNA HEPA-ZAF MVEM-21 ROERIBEC CAMOPLEX LYSINE WERIFIT WITH LYSINE AMROBION DEXIPLEX-F ENGLISH-PLEX-L MYTON-S MYTON-S MYTON-S LISKOPLEX LISKOPLEX LISKOPLEX MULTIMIN MULTIMIN MULTIMIN MULTIMIN VITABEX C VITAZYME PLEXOVIT PLEXOVIT PLEXOVIT VITONE ACE-BEX NEUROBEDOXINE NEUROBEDOXINE SCHAZOOS B-TONIC ADENOFORT ADENOFORT ALINAMIN-F KARMAPLEX SANZYM ORAVIT-H PLEXOVIT-L VASEDEX-L VIKONON FORTE TROVIT AZEE-VIT ENERGY CYANORIN FORTE OPALEX MULTI OPALEX MULTI SEVENSEAS MVM SEVENSEAS MVM SEVENSEAS MVM OPALEX EXTRA OPALEX EXTRA VI-CAPS ARDIPLEX ZYGEST NEUROBEDOXINE PLUS DELMIN DELCOBEX VIONEURIN FORTE VIONEURIN FORTE ENERGIN VITACOMPON MAZIVIT M NEUROTONE NEUROTONE APPEVIT TOXINIL WILPLEX CYANOPLEX SOLUTION 1 DILCOPLEX DILCOPLEX DILCOPLEX DILCOPLEX ELKOPLEX EROGLOBIN EROGLOBIN CALCEPLEX FORTE DAVIPLEX GENIPLEX MEGA-V AMVIT AMVIT BLOMIC ENEMIK ENEMIK HAEM NUTRICAP-M THERON-F THERON-F THERON-F ZYVIT LYSOMEL FEMOCAL PLUS NEURO VITA BRUCIPIN MULTONIC HEMOCAL RENAPLEX K-CEE PLUS LYBECEN HONEYPLEX EFFECO TONIC MEGAZYME PHOZFODEX EFER-VIT CAL-V-CON SUPERR-7 SUMMERVITA SUMMERVITA TROVIT-F VIDAYLIN-M VIDAYLIN-M IRONMIN ALFAVIT ALFAVIT POLYBION N GROVIT-B GENATOSAN PLUS IRON VIDAYLIN-L SUPRADYN RUBJOVIT AMROTON AMROTON MULTIVITAMIN VITAG DIABETONE MYFER MYFER ENGVIT-L ENGVIT-L ENGVIT-L LYSOTOP HEPATOVIT POLY CAL PLUS LAWRPLEX UNIBEX-T SURGIBION SURGIBION BETALUX B.COMPLEX B.COMPLEX B.COMPLEX MULTITINE NEUROPLEX THIAMINE HYDROCHLORIDE B.COMPLEX FORTE B.COMPOUND MULTITONE MAZIVIT VEROMIN-T NEVRAMIN NEVRAMIN SEPTOPLEX NEUROXOL PREGNATAL POLYBION STRONG GEOVIT FORTE GEOVIT FORTE ENGRAN ESSENTIALE INJ VIFER NEZATON RIB C SEMOGLOBIN THERAPLEX QUANTUM GOLD QUANTUM SUPER IBERET 500 GRADUMET IBERET 500 GRADUMET NEUTROBION NEUROVIT-M WILGRAN-M Y-GOGIN M-BROVIT M-BROVIT OLIVIT OLIVIT OLIVIT BECOSCOT POLYBION FORTE C POLYBION FORTE C VIDAYLIN-T MULTINA MAX MULTINA MAX MULTINA MAX EUROBION MYVIT-T DIVASAS VITACON EUROPLEX EUROVIT COMBIPLEX FORTE KIDS CAPROVIT ALVIDOX WELMATON ACTIVAL VITIRON C ZINTABION ZOVIT NUTRAN BENTABION BENTABION BENTAPLEX BENTAPLEX BECE VIT BECE VIT BODIBEC FERATONIC-VIT CORAMIN-G ACTIVITAL ENERGY PLUS FFERROPRO REMO MULTIVITAMIN REMOPLEX REMOPLEX REMOPLEX REMOPLEX MB-VITA TAZIN TAZIN THERIN VIT MULTEX MULTEX SIGPA THIABION VITATHERA-C VITATHERA AWARDIN PLUS KAYCIPLEX M. BROPLEX M. BROPLEX M. BROPLEX M. BROPLEX GERIATRIC PHARMATON GERIATRIC PHARMATON POLYBION Z PREGNA CARE HEMOTIN ALVIT F CLOMVIT-F SPECTRA CONUS ENGOR EVIVAL FITERNA NYSOBION ENVIT G-VIT REGNUM GERICAP
Adult Dose
Dose: 100 to 300 mg
Single Dose: 200 (200)
Frequency: 24 hourly
Route: PO,IM
Instructions: IV doses should be administered slowly atleast over 20 min to reduce Idiosyncratic reactions
Neonatal
Dose: 0.625 mg/kg
Single Dose: 0.62 (0.625)
Frequency: 24 hourly
Route: Intramuscular
Instructions:
Paedriatic
Dose: 1 mg/kg
Single Dose: 1 (1)
Frequency: 24 hourly
Route: Intra Muscular
Instructions: -
Characteristics
Thiamine HCl (Vitamin B1) also known as Fursultamine, Fursultamine. . It is of Synthetic origin and belongs to Thiopyrimidine. It belongs to Vitamin, Water Soluble pharmacological group.The Molecular Weight of Thiamine HCl (Vitamin B1) is 337.30. It is strongly acidic drug, 4.24% solution of the drug is isotonic and Its pKa is 4.8.
Contraindications
Thiamine HCl (Vitamin B1)
Effects
The severe or irreversible adverse effects of Thiamine HCl (Vitamin B1), which give rise to further complications include Nausea, Urticaria, Gi bleeding, Angioneurotic edema, Restlessness, Pruritis, Pulmonary edema, Hemorrhage, Cyanosis, Anaphylactic reactions.The symptomatic adverse reactions produced by Thiamine HCl (Vitamin B1) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Ataxia, Nausea, Anorexia, Lethargy, SweatingX, SomnolenceX, Faintness, Heaviness, Soreness.
Indications
Thiamine HCl (Vitamin B1) is primarily indicated in conditions like Lung cancer and pancreatic cancer, Mild chronic deficiency, Severe deficiency, Thiamine deficiency prophylaxis, Thiamine deficiency treatment.
Interactions
Thiamine HCl (Vitamin B1) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAluminium Hydroxide and OxideAntacids may lower thiamin levels in the body by decreasing absorption and increasing excretion or metabolism.Amiloride (HCl)Amiloride (HCl) have been associated with decreased thiamin levels in the body by increasing urinary excretion and possibly by decreasing absorption and increasing metabolism.BumetanideBumetanide have been associated with decreased thiamin levels in the body by increasing urinary excretion and possibly by decreasing absorption and increasing metabolism.ChlorthalidoneChlorthalidone have been associated with decreased thiamin levels in the body by increasing urinary excretion and possibly by decreasing absorption and increasing metabolism.Estradiol (Valerate)Estradiol (Valerate) may decrease levels of some B vitamins, vitamin C, and zinc in the body.Estrogens ConjugatedEstrogens Conjugated may decrease levels of some B vitamins, vitamin C, and zinc in the body.FluorouracilPeople receiving fluorouracil-containing chemotherapy regimens may be at risk for developing symptoms and signs of thiamin deficiency.Magnesium CarbonateAntacids may lower thiamin levels in the body by decreasing absorption and increasing excretion or metabolism.Magnesium Oxides and HydroxidesAntacids may lower thiamin levels in the body by decreasing absorption and increasing excretion or metabolism.Metformin (HCl)Metformin (HCl) may reduce thiamine activity.Phenobarbital SodiumBarbiturates may lower thiamin levels in the body by decreasing absorption and increasing excretion or metabolism.PhenobarbitoneBarbiturates may lower thiamin levels in the body by decreasing absorption and increasing excretion or metabolism.TriamtereneTriamterene have been associated with decreased thiamin levels in the body by increasing urinary excretion and possibly by decreasing absorption and increasing metabolism.Vecuronium (Br) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 40°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Warnings
If patients have had a bad reaction (skin reaction, difficulty in swallowing or difficulty in breathing) to thiamine in the past, inform the doctor. Except in doses greater than recommended, thiamine is considered safe for use during pregnancy or lactation.
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