Tetracosactrin

Tetracosactrin is a synthetic polypeptide. Tetracosactrin is used as a test of adrenal function and for the treatment of inflammatory or degenerative disorders.


Brands
Adult Dose
Dose: 3.57 ug/kg
Single Dose: 3.6 (3.57)
Frequency: As recommended.
Route: IM
Instructions: For Once or As Required
Neonatal
Dose: 36 ug/kg
Single Dose: 36 (36)
Frequency: As recommended.
Route: Intramuscular
Instructions: Single dose
Paedriatic
Dose: 25 ug/kg
Single Dose: 25 (25)
Frequency: As recommended.
Route: Intra Muscular
Instructions: Single Dose
Characteristics
Tetracosactrin also known as Tetracosactide, Tetracosactide. . It is of Synthetic origin and belongs to Polypeptide. It belongs to ACTH agonist pharmacological group on the basis of mechanism of action and also classified in Diagnostic Aids pharmacological group.The Molecular Weight of Tetracosactrin is 2993.50.
Contraindications
'Tetracosactrin is contraindicated in conditions like Asthma,Cushing''s syndrome,Heart failure,Peptic ulcer,Psychosis,Infections,Hypersensitivity.'
Effects
The severe or irreversible adverse effects of Tetracosactrin, which give rise to further complications include Hypertension, Diabetes, Osteoporosis, Growth retardation.Tetracosactrin produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Tetracosactrin therapy.The signs and symptoms that are produced after the acute overdosage of Tetracosactrin include Hyperglycemia.The symptomatic adverse reactions produced by Tetracosactrin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Pain, Bruising, Acne, Hirsutism, Menstrual irregularity, Skin atrophy.
Indications
'Tetracosactrin is primarily indicated in conditions like Crohn''s disease, Investigation of adrenocortical function, Juvenile chronic arthritis, Multiple sclerosis, Osteoarthritis, Rheumatoid arthritis, Ulcerative colitis.'
Interactions
No data regarding the interactions of Tetracosactrin was found.
Interfrence
Radioimmunoassay of endogeous ACTH
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj, IM Inj Store in refrigerator. Protect from Sunlight.
Warnings
Avoid tetracosactrin in patients with history of allergic disorder such as asthma. Self administration is not recommended.
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