S-CHOLINE SUXAL SUXAMETHONIUM LEPTOSUCCIN LEPTOSUCCIN SUCCICHOLINE SUXAMETHONIUM PANTOLAX SUCCIN SUXA-CHOLINE ARILAX SUXINIUM SUXINIUM SUXINIUM MIOFLEX MUSELAX MUSELAX SUMETH DEXAL SUXAM THONIUM SUCICHOL B-METHO SUXAGEN NEURONIUM SOTHONUM MOLVCOM MOLVCOM ZUSELAX ZUSELAX

Dose: 0.1 to 0.2 mg/ kg
Single Dose: 0.15 (0.15)
Frequency: As recommended.
Route: IV
Instructions: Usually produce muscle relaxation for 1-3 Min.

Dose: 2 mg/kg
Single Dose: 2 (2)
Frequency: As recommended.
Route: Intravenous
Instructions: As required

Dose: 1 mg/kg
Single Dose: 1 (1)
Frequency: As recommended.
Route: Intravenous
Instructions: As required

belongs to Acetylcholine. It belongs to Cholinergic nicotinic antagonist pharmacological group on the basis of mechanism of action and also classified in Muscle Relaxants pharmacological group.The Molecular Weight of Suxamethonium (Cl) is 361.30. Its pKa is not relevant.

Suxamethonium (Cl) is contraindicated in conditions like Malignant hyperthermia,Myopathy,Eye injuries.

The severe or irreversible adverse effects of Suxamethonium (Cl), which give rise to further complications include Increased intragastric pressure, Increased IOP (intraocular pressure).Suxamethonium (Cl) produces potentially life-threatening effects which include Pulmonary edema, Respiratory depression, Hyperkalemia, Cardiac arrhythmias, Increased intracranial pressure, Myalgia, Pulmonary hemorrhage, Myoglobinemia, Increased intraocular pressure. which are responsible for the discontinuation of Suxamethonium (Cl) therapy.

Suxamethonium (Cl) is primarily indicated in conditions like Muscle relaxation (rapid onset, short duration), Muscular spasm, Neuromuscular blockade, and can also be given in adjunctive therapy as an alternative drug of choice in Anesthesia, Insomnia, Surgery.

Suxamethonium (Cl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlfentanil (HCl)AprotininAtracurium (Besylate)BambuterolBambuterol enhances effects of Suxamethonium.ChloroquineCocaineCyclophosphamideCyclophosphamideDigoxinDistigmine (Br)D-PantothenolPantothenol should be given cautiously with Suxamethonium (Cl) because the risk of anaphylactic shock increases with repeated administration of Pantothenol.Edrophonium (Cl)EtherIsofluraneLignocaineLignocaineLithiumMagnesium Oxides and HydroxidesMagnesium Oxides and HydroxidesMagnesium SulphateMannitolMetacycline (HCl)may prolong neuromascular blockadeMetriphonateInsectisides and anticholinesterase.Mivacurium (Cl)OxybuprocaineOxytocinPentamidinePhenelzinePhysostigminePralidoximeProcainamide (HCl)Promazine (HCl)QuinidineQuinineRivastigmineSufentanil (Citrate)Trimetaphan (Camsylate)Vecuronium (Br) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Increased Serum Potassium Level

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store in refrigerator. Do not Freeze.

Avoid suxamethazone in patients with burns, massive trauma, renal impairment, severe long lasting sepsis and severe hyperkalaemia, sensitivity to drug, eye injury or glaucoma. It should be used with caution in patients with bone fractures, cardiac or respiratory disease. Dose of neuromuscular blocking agent need to be clearly titrated for individual patients according to their response; monitoring of the degree of block is recommended in order to reduce the risk of overdosage. Patients who have received neuromuscular blocker should always have their respiration assisted or controlled until the drug has been inactivated or antagonized.