SULPADE LEVOMA LEVOMA

Dose: 200 to 400 mg
Single Dose: 300 (300)
Frequency: 12 hourly
Route: PO
Instructions: Max.800 mg daily.

Dose: Not indicated in this age group
Single Dose:
Frequency:
Route:
Instructions:

. It is of Synthetic origin and belongs to Benzamide. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group.The Molecular Weight of Sulpiride is 341.40. Its pKa is 8.9.

Sulpiride is contraindicated in conditions like Epilepsy,Phaeochromocytoma,Porphyria.

The severe or irreversible adverse effects of Sulpiride, which give rise to further complications include Tardive dyskinesia.Sulpiride produces potentially life-threatening effects which include Hepatitis, Malignant neuroplastic syndrome, Hypertensive crises. which are responsible for the discontinuation of Sulpiride therapy.The signs and symptoms that are produced after the acute overdosage of Sulpiride include Hypotension, Confusion, Agitation, Restlessness, Extrapyramidal effects.The symptomatic adverse reactions produced by Sulpiride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Excitement, Anxiety, Parkinsonism, Akathisia, Acute dystonia, Elevated alkaline phosphatase, Mood swings, Leukopenia, Elevated aminotransferase.

Sulpiride is primarily indicated in conditions like Control of muscarinic side-effects of neostigmine, Depression, Psychosis, Schizophrenia.

Sulpiride is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAmitriptyline (HCl)Buspirone (HCl)Cimetidine (HCl)Clomipramine (HCl)CocainedeferoxamineDisulfiramNaltrexonePiperazineSucralfate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Test for Estimating Glucose and Cholestrole Conc. in Serum

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 25°C.

Sulpiride should be given with care to manic or hypomanic patients in whom it may exacerbate symptoms. It should be used with care during pregnancy, avoid use during lactation. It should be used with caution in patients with impaired renal function.