SINDAM MALSIDAR MALSIDAR MALSIDAR MALADRIN MALAGON MALAGON MALADAR MALADAR MALADAR FALARAX FALARAX MALARKIL MALARKIL MINISH MINISH MALACURE MALACURE ANTIFOCINE ANTIFOCINE MALIDAR MALIDAR SULDOXIN MALAREST MALAREST MALA NIL MALA NIL FANSIDAR FANSIDAR FANSIDAR FANSIMEF RIDMAL RIDMAL MELOFIN MELOFIN MELOFIN EUDAR HAMADAR HAMADAR HAMADAR MALARINA MALARINA MALARINA FAVAX FAVAX METAFIN FALCICURE FALCICURE SCOTS ANTIMALARIAL FANSIWIL MALARIDOX MALAFAR MALAFAR IRENE SULFABEN SULFABEN SULFABEN MATACIN MALAYREX NEOSIDAR NEOSIDAR SULFADAR SULFADAR METHODOX METHODOX FANSIQIN NO-MALAR MALAVIS MALAVIS FOLIDAR ANTIPLAST FADOPRIM FADOPRIM FADOPRIM GAMETANIL GAMETANIL MALADOX PLASMONIL FALCIPAR FALCIPAR EPLAQUIN DOXAMINE FANSIMATE MALASUNATE FIDOXINE SULPHA-P SULPHA-P ARTESUL ARTESUL PLASMOXIT FANSI PLUS SP-MAL SULPINE SAF-SP SULFALARIA ARTEDOXIN ARTEDOXIN P GEN ART SP GENART-SP SINDA-MP SINDA-MP MASFANDAR MIRIADAR MIRIADAR ROTAPRIM GERIDAR GERIDAR NEO-MAL

Dose: 1500 mg
Single Dose: 1500 (1500)
Frequency: As recommended.
Route: PO
Instructions: Single dose in combination with Pyrimethamine 75 mg.

Dose: 25 mg/kg
Single Dose: 25 (25)
Frequency: As recommended.
Route: Oral
Instructions: Single dose

Dose: 33.33 mg/kg
Single Dose: 33 (33.33)
Frequency: As recommended.
Route: Oral
Instructions: For Once, Dose for Paeds of 4-12 Yrs.

Sulfadoxine also known as Sulformethoxine, Sulformethoxine. . It is of Synthetic origin and belongs to Sulphonamide. It belongs to Dihyropteroate synthetase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group.The Molecular Weight of Sulfadoxine is 310.30. Its pKa is 6.3.

Sulfadoxine is contraindicated in conditions like Blood dyscrasias,Renal diseases,Hypersensitivity.

The severe or irreversible adverse effects of Sulfadoxine, which give rise to further complications include Hepatitis, Pneumonitis.Sulfadoxine produces potentially life-threatening effects which include Mucocutaneous reaction. which are responsible for the discontinuation of Sulfadoxine therapy.The signs and symptoms that are produced after the acute overdosage of Sulfadoxine include Nausea, Vomiting, Convulsions, Excitation, Anorexia, Hematological toxicity.The symptomatic adverse reactions produced by Sulfadoxine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Fever, Rashes, Stomatitis, Pruritus, Photosensitivity, Nausea and vomiting, Orthostatic hypotension, Feeling of fulness, Hepatic granulomata, Polyneuritis.

Sulfadoxine is primarily indicated in conditions like Malaria prophylaxis, Severe falciparum malaria, Toxoplasmosis, and can also be given in adjunctive therapy as an alternative drug of choice in Cholera, Pneumonia.

Sulfadoxine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementChloroquineChloroquineMefloquine (HCl)Phenytoin (Na)Thiopentone (Na)TrimethoprimWarfarin (Na)Xylitol These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Complete blood cell count

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Sulfadoxine should be used only if clearly needed during pregnancy. It should be used with caution in patients with pre-existing blood disorders, anemia, liver disease, kidney disease, severe allergies, asthma or a history of seizures or any allergy, especially to sulfa medications.