SULPHADIMIDINE SULPHADIMIDINE SULPHADIMIDINE SULPHADIMIDINE DEMISUL SULPHADIAMIDINE SULPHADIMIDINE SODIUM SULPHADIMIDINE SODIUM SULPHADIAMIDINE ANITMALA DEXIDON METAFAN METAFAN

Dose: 2 g
Single Dose: 2 (2)
Frequency: As recommended.
Route: PO
Instructions: Single dose.

Dose: 25 mg/kg
Single Dose: 25 (25)
Frequency: 6 hourly
Route: Intra Muscular
Instructions: Maintenance, As Required

Dose: 25 mg/kg
Single Dose: 25 (25)
Frequency: 6 hourly
Route: Intra Muscular
Instructions: Maintenance, As Required

. It is of Synthetic origin and belongs to Sulphonamide. It belongs to Dihyropteroate synthetase inhibitor pharmacological group on the basis of mechanism of action and also classified in Folic Acid Inhibitor, Sulphonamide pharmacological group.The Molecular Weight of Sulfadimidine is 278.30. Its pKa is 7.4.

Sulfadimidine is contraindicated in conditions like Renal failure,Porphyrias.

The severe or irreversible adverse effects of Sulfadimidine, which give rise to further complications include Thrombocytopenia, Hepatitis, Pancreatitis, Cholestatic jaundice, Hemolytic anemia, Hemolytic anemia, Epidermal necrolysis, Vasculitis, Agranulocytosis, Iritis, Retinal hemorrhage, Optic neuropathy, Pulmonary eosinophilia, Arteritis.Sulfadimidine produces potentially life-threatening effects which include Stevens Johnson syndrome. which are responsible for the discontinuation of Sulfadimidine therapy.The symptomatic adverse reactions produced by Sulfadimidine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Rashes, Hematuria, Nausea and vomiting, Cyanosis, Leukopenia, Crystalluria, Anuria.

Sulfadimidine is primarily indicated in conditions like Meningitis, Urinary tract infection.

No data regarding the interactions of Sulfadimidine was found.

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab, Susp, Inj

Allergic reaction to sulfa drugs may occur sometimes. Elderly adults are especially sensitive to the effects of sulfonamides. Severe skin and blood disorders may be more likely to occur in the elderly. The adverse effects may also be more likely to occur in patients who are taking diuretics together with these drugs