Sufentanil (Citrate)

Sufentanil (Citrate) is opiod analgesic. Sufentanil (Citrate) is given parentrally as an adjunct in anesthesia and as a primary anesthetic drug in procedurers requiring assisted ventilation. Sufentanil (Citrate) is highly lipid-soluble and the onset of action is rapid with a more rapid recovery than fentanyl..

Brands
Adult Dose
Dose: 0.1 ug/kg
Single Dose: 0.1 (0.1)
Frequency: As recommended.
Route: IV
Instructions: As Required
Neonatal
Paedriatic
Dose: 10 to 25 ug/kg
Single Dose: 18 (17.5)
Frequency: As recommended.
Route: Intavenous
Instructions: As required
Characteristics
. It is of Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents and Analgesic-Narcotic pharmacological group.The Molecular Weight of Sufentanil (Citrate) is 578.70. Its pKa is 8.01.
Contraindications
Sufentanil (Citrate) is contraindicated in conditions like Hypovolaemia,Respiratory depression.
Effects
The severe or irreversible adverse effects of Sufentanil (Citrate), which give rise to further complications include Tonic-clonic seizures.Sufentanil (Citrate) produces potentially life-threatening effects which include Respiratory depression. which are responsible for the discontinuation of Sufentanil (Citrate) therapy.The symptomatic adverse reactions produced by Sufentanil (Citrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea and vomiting.
Indications
Sufentanil (Citrate) is primarily indicated in conditions like Pain, and can also be given in adjunctive therapy as an alternative drug of choice in Anesthesia.
Interactions
Sufentanil (Citrate) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAtracurium (Besylate)HalothaneSuxamethonium (Cl)Thiopentone (Na)Vecuronium (Br)VORICONAZOLEVoriconazole may increase the serum concentration of sufentanil by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store at room temperature. Do not Freeze. Protect from Sunlight.
Warnings
Sufentanil should be used with caution in patients with central nervous system (CNS) depression, convulsive disorder, ulcerative colitis, fever, recent gastrointestinal (GI) surgery, bradyarrhythmias, supraventricular tachycardia, pulmonary diseases. Patients should exercise caution while driving or performing tasks requiring alertness because it may produce drowsiness.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.