Dose: 1.14 mg/kg
Single Dose: 1.1 (1.14)
Frequency: 12 hourly
Route: PO
Instructions: Initial

Dose: Not used in this age group
Single Dose:
Frequency:
Route:
Instructions:

Dose: Not used in children
Single Dose:
Frequency:
Route:
Instructions:

. It is of Synthetic origin and belongs to Sulphonamide. It belongs to Beta adrenergic antagonist pharmacological group on the basis of mechanism of action and also classified in Anti arrhythmic agents pharmacological group.The Molecular Weight of Sotalol (HCl) is 308.80. Its pKa is 8.3, 9.8.

Sotalol (HCl) is contraindicated in conditions like Acidosis,Bronchospasm,Atrioventricular block,Diabetic ketoacidosis.

The severe or irreversible adverse effects of Sotalol (HCl), which give rise to further complications include Retroperitoneal fibrosis.Sotalol (HCl) produces potentially life-threatening effects which include Ventricular fibrillation, Ventricular tachycardia, Torsades de pointes. which are responsible for the discontinuation of Sotalol (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Sotalol (HCl) include Bradycardia, Hypotension, Cardiac arrhythmias, Cardiac failure.The symptomatic adverse reactions produced by Sotalol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Insomnia, Lassitude.

Sotalol (HCl) is primarily indicated in conditions like Cardiac arrhythmia, Hypertension, Ischaemic heart disease, Life-threatening arrhythmias including ventricular tachyarrhythmias, Prophylaxis of paroxysmal atrial tachycardia or fibrillation, and can also be given in adjunctive therapy as an alternative drug of choice in Myocardial infarction, Thyrotoxicosis.

Sotalol (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAmiodarone (HCl)Amiodarone may enhance the bradycardic effect of Sotalol. Possibly to the point of cardiac arrest. ADVICE: Avoid concomitant use or only undertaken with caution and apprppriate monitoring.MajorAmitriptyline (HCl)AmoxapineIncreased risk of ventricular arrhythmia when Amoxapine given with Sotalol.ArtemisininAstemizoleBendrofluazideChlorothiazideChlorthalidoneDisopyramideDisopyramideDothiepin (HCl)EnfluraneErythromycinEtherFexofenadineThe Concomitant use of both drugs can lead to QT interval prolongationHalofantrine (HCl)HydrochlorothiazidePentamidinePioglitazonePolythiazideProcainamide (HCl)PropyliodoneConcurrent use may potentiate the risk of severe hypotensive or hypersensitivity reactions.ModeratePatients who have received beta-blockers should be closely monitored for adverse reactions to iodinated contrast media.Protriptyline (HCl)QuinidineVORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or monitor for QTc prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Falsely elevated levels of urinary metanephrine

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Heat.

Sotalol should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with pre-existing kidney disease, heart disease, lungs disease, asthma, emphysema, thyroid disease, diabetes or if have any allergy.