Sorbitol

Sorbitol is a six carbon sugar alcohol formed by reduction of the carbonyl group of glucose and occuring naturally in a variety of fruits. Sorbitol is a precursor of fructose in seminal plasma.


Adult Dose
Dose: 30%
Single Dose: 30 (30)
Frequency: As recommended.
Route: IV Inf
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Sugar Alcohol. It belongs to Nutrients and Vitamins pharmacological group on the basis of mechanism of action and also classified in Parenteral Nutrition pharmacological group.The Molecular Weight of Sorbitol is 182.20. It is weakly acidic drug, 5.48% solution of the drug is isotonic and Its pKa is 13.7.
Contraindications
Sorbitol is contraindicated in conditions like Renal failure,Hepatic failure,Inborn errors of metabolism.
Effects
The severe or irreversible adverse effects of Sorbitol, which give rise to further complications include Sinus tachycardia, Seizures, Urinary retention, Metabolic acidosis, Pulmonary congestion.Sorbitol produces potentially life-threatening effects which include Increased blood lactate. which are responsible for the discontinuation of Sorbitol therapy.The signs and symptoms that are produced after the acute overdosage of Sorbitol include Diuresis, Hyperosmolarity.The symptomatic adverse reactions produced by Sorbitol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Nausea, Vomiting, Abdominal pain, Blurred vision, Facial flushing, SweatingX, Xerostomia.
Indications
Sorbitol is primarily indicated in conditions like Transurethral surgery, Urinary bladder irrigation, and can also be given in adjunctive therapy as an alternative drug of choice in Constipation.
Interactions
No data regarding the interactions of Sorbitol was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inf Store in a well closed container.
Warnings
Sorbitol should be used with caution in patients with known subclinical diabetes mellitus. It should be given with extreme caution to patients with impaired kidney function or severe liver damage, cardiopulmonary disease, hyponatremia and in uremia.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.