HUMATROPE HUMATROPE HUMATROPE NORDITROPIN GENOTROPIN HHT EUTROPIN

Dose: 0.018 IU/ kg
Single Dose: 0.018 (0.018)
Frequency: As recommended.
Route: SC
Instructions: As a single dose. For the treatment of growth failure or growth hormon deficiency. Maximum dose 0.0375 IU/kg/day.

Dose: 0.166 to 0.233 IU/kg
Single Dose: 0.2 (0.1995)
Frequency: 8 hourly
Route: Intra Muscular
Instructions: -

Dose: 0.166 to 0.233 IU/kg
Single Dose: 0.2 (0.1995)
Frequency: 8 hourly
Route: Intra Muscular
Instructions: -

Somatropin also known as Human Growth hormone. . It is of Synthetic origin and belongs to Amino Acid. It belongs to Growth hormone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones pharmacological group.The Molecular Weight of Somatropin is 22000.00. Its pKa is 6.0 - 7.5.

Somatropin is contraindicated in conditions like Diabetes mellitus.

The symptomatic adverse reactions produced by Somatropin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Urticaria, Arthralgia, Edema, Lipoatrophy.

Somatropin is primarily indicated in conditions like Adult growth hormone deficiency, Chronic renal failure, Deficiency of growth hormone in children, Gonadal dysgenesis (turner syndrome), Growth hormone deficiency, Severe chronic neutropenia, Turners syndrome.

Somatropin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAcarboseCorticotropinSomatropin administration may alter the clearance of Corticotropin.Cortisone (Acetate)Somatropin administration may alter the clearance of Cortisone (Acetate).Cyclosporin ASomatropin administration may alter the clearance of Cyclosporin A.DeflazacortEstrogens ConjugatedBecause oral estrogens may reduce the serum IGF-I response to somatropin treatment, girls and women receiving oral estrogen replacement may require greater somatropin dosagesInsulinPatients with diabetes mellitus who receive concomitant treatment with somatropin may require adjustment of their doses of insulin and/or other hypoglycemic agentsInsulin GlulisineSomatropin, corticosteroids, niacin, diuretics, sympathomimetic agents (e.g., epinephrine, albuterol, terbutaline), phenothiazine derivatives, thyroid hormones, progestogens (e.g., in oral contr.aceptives), protease inhibitors, and atypical antipsychotics may reduce the blood-glucose-lowering effect.ThymomodulinThymomodulin may show synergism with Somatropin. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Immunoassay of Endogenous Growth Hormone

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store in refrigerator. Do not Freeze. Protect from Sunlight.

Somatropin should be used with caution in patients with history of tumors (cancer), any allergy, especially drug allergies, diabetes, thyroid problems or back problems (scoliosis). This medication should be used only when clearly needed during pregnancy.