Sodium Bicarbonate

Sodium bicarbonate is the monosodium salt of carbinic acid. It is used as an alkalinizing agent in the treatment of metabolic acidosis. It causes alkinization of urine and therefore can be given to relieve the discomfort in mild urinary tract disorders. It neutralizes the acid in gastro-intestinal tract, therefore frequently included in antacid preparations.


Brands
CITRO SODA CARMINATIVE MIXTURE SODIUM BICARBONATE BLISS CARMA CARMINATIVE MIXTURE CARMINATIVE MIXTURE HICARMA MIXTURE KYKIL MEYLON SODAMINT SODAMINT CARMINATIVE MIXTURE CARMINATIVE MIXTURE SODAMINT CARMINATIVE MIX (ADULTS) CARMINATIVE MIXTURE CARMINATIVE MIXTURE AMINOVEL-600 SODEX SODEX SODEX SODEX SODEX CARMIX CARMIX GAVISCON GAVISCON GAVISCON SODIUM BICARBONATE SODIUM BICARBONATE ENCID ENCID ENCID ENCID ORASAL-F GRIPE WATER GRIPE WATER SODIUM BICARBONATE ENO REGULAR ENO REGULAR MOMS GRIPE WATER SHOLLS GRIPE WATER INFANTS CARMINATIVE CARMINATIVE MIX (INFANT) ORASAL CALCEPLEX FORTE BLISS GRIPE MIXTURE ONE SODA GLYCERINE CARMINATIVE MIXTURE CARMINATIVE MIXTURE FROOTA FRUIT FROOTA FRUIT WILSONS FRUIT SALT MEIJI GRIPE WATER ENO LEMON ENO LEMON ENO ORANGE ENO ORANGE PROCAR MIX ADULT CAC 1000 PLUS SECURE JR GEOFMAN SP GEOFMAN SP SODIUM BI CARBONATE SODA GLYCERIN EAR DROPS SODCIT KEMYCARMINA SOBONATE BICARBONATE RELEEF FRUIT SALT RELEEF FRUIT SALT AMINOLEBAN ORAL GASTROCID REMOCARMA MIXTURE REMOCARMA MIXTURE MB-GRIPE WATER NEUSEC NEUSEC NEUSEC NEUSEC SODAMINT COLIC ALGIMAZ SODAMINT SODA MINT SODA MINT OMNAT PLUS OMNAT PLUS OMNAT PLUS OMNAT PLUS OMCED-S RISEK INSTA RISEK INSTA NEUSEC PLUS NEUSEC PLUS NEUSEC PLUS NEUSEC PLUS BIOS BIOS BIOS BIOS OMEPRAFAST OMEPRAFAST OMEPID OMEPID ZEGERID OPEROS OPEROS MAPRA MAPRA OMI-B OMI-B OMI-B OMI-B MEP-B MEP-B MEP-B MEP-B NOAZOL PLUS NOAZOL PLUS NOAZOL PLUS NOAZOL PLUS OMEZAC PLUS OMEZAC PLUS OMEZAC PLUS OMEZAC PLUS SANTE PLUS SANTE PLUS SOBICARB SOBICARB ERIFASS ERIFASS MAGFAST MAGFAST OMEGA OMEGA OMEGA OMEGA OMEPROWAN PLUS OMEPROWAN PLUS OMEPROWAN PLUS OMEPROWAN PLUS OMEZONATE OMEZONATE OMEZONATE OMEZONATE OPEPZOLE OPEPZOLE OPEPZOLE OPEPZOLE ERIFASS D ERIFASS D MAGFAST D MAGFAST D ZEGERID PLUS OMEGA RAPID OMEGA RAPID OMEGA RAPID OMEGA RAPID FAAST FAAST OMEFAST AMPRA AMPRA AMPRA AMPRA CITROVEL ESCAR ESCAR GASCAD MESO OMENATE OMENATE OMENATE-D OMENATE-D OMSOD OMSOD OMSOD OMSOD OPIZOL OPIZOL OZOP SB OZOP SB PRAMAX PRAMAX PRAMAX PRAMAX PRENAT PRENAT PRENAT PRENAT SODAZAF SODONATE VIVID CAPSULE VIVID CAPSULE BIMEP ZOLTAR INSTA ZOLTAR INSTA ZOLTAR INSTA ZOLTAR INSTA RULING PLUS RULING PLUS RULING PLUS RULING PLUS EPRACO EPRACO MOVCOL OMEFAST PLUS OMREL PLUS OMREL PLUS OMREL PLUS OMREL PLUS OZOPMAX OZOPMAX OMEXIA OMEXIA OMNIMINT OMNIMINT XIFT XIFT
Adult Dose
Dose: 8.40%
Single Dose: 8.4 (8.4)
Frequency: As recommended.
Route: IV
Instructions: As required
Neonatal
Dose: 1 to 2 mg/kg
Single Dose: 1.5 (1.5)
Frequency: As recommended.
Route: Slow IV
Instructions: Once or As Required
Paedriatic
Dose: 1 to 2 mg/kg
Single Dose: 1.5 (1.5)
Frequency: As recommended.
Route: Slow IV
Instructions: Once or As Required
Characteristics
. It is of Synthetic origin and belongs to Sodium salt. It belongs to Minerals and Electrolytes pharmacological group on the basis of mechanism of action and also classified in Antacids and Antiflatulent pharmacological group.The Molecular Weight of Sodium Bicarbonate is 84.01. It is weakly alkaline drug, 1.39% solution of the drug is isotonic.
Contraindications
Sodium Bicarbonate is contraindicated in conditions like Hypocalcaemia,Metabolic alkalosis,Respiratory alkalosis,Hyperosmolarity,Hypoventilation,Chloride depletion.
Effects
The severe or irreversible adverse effects of Sodium Bicarbonate, which give rise to further complications include Hypokalemia, Seizures, Metabolic alkalosis, Lactic acidosis.Sodium Bicarbonate produces potentially life-threatening effects which include Pulmonary edema, Hyperventilation, Paradoxical acidosis, Volume overload. which are responsible for the discontinuation of Sodium Bicarbonate therapy.The symptomatic adverse reactions produced by Sodium Bicarbonate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Necrosis, Abdominal pain, Sloughing, Chemical cellulitis, Ulceration, Hypernatremia, Tetany, Reaction at injection site.
Indications
Sodium Bicarbonate is primarily indicated in conditions like Cardiopulmonary resuscitation, Chronic acidotic states, Hyperkalaemia, Metabolic acidosis, Muscle spasm (acute), Relief of discomfort in mild UTIs, Renal acidosis or in severe metabolic acidosis of any origin, Severe shock due for example to cardiac arrest, and can also be given in adjunctive therapy as an alternative drug of choice in Cardiac arrest, Urinary alkalinization.
Interactions
Sodium Bicarbonate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAscorbic AcidBumetanideCefpodoximeChlortetracycline (HCl)Demeclocycline (HCl)DoxycyclineEphedrineErythromycinFloxacillin (Na)Frusemide or FurosemideLithiumMetacycline (HCl)MethadoneMinocycline (HCl)Oxytetracycline (Dihydrate)Potassium SaltsPseudoephedrine (HCl)QuinidineTetracycline (HCl)Tetracycline (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
False +ve Labstix Test for Urinary Protein Gastric Acid Secretory Function Test
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Inj, Powder Store Below 40°C. Protect from Sunlight, Moisture and Heat.
Warnings
Avoid overdose and alkalosis by giving repeated small doses. Sodium bicarbonate should be used with caution in patients of CHF (congestive heart failure). It should be used with caution in patients with stomach disorders or allergies.
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