Silver Nitrate

Silver Nitrate is antiseptic, disinfectant, astringent and a caustic agent. Silver ion, as an antiseptic has a very broad spectrumespecially against those organism that commonly invade burn wounds, therefore silver nitrate is successfully in the management of severe burns.


Brands
Adult Dose
Dose: 0.50%
Single Dose: 0.5 (0.5)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Neonatal
Dose: 1%
Single Dose: 1 (1)
Frequency: As recommended.
Route: Topical
Instructions: As required
Paedriatic
Characteristics
. It is of Natural origin and belongs to Silver Salt. It belongs to Dermatological-Caustic pharmacological group on the basis of mechanism of action and also classified in Dermatological Products pharmacological group.The Molecular Weight of Silver Nitrate is 169.90. It is weakly acidic drug, 2.74% solution of the drug is isotonic.
Contraindications
Silver Nitrate is contraindicated in conditions like Wounds,Broken skin,Cuts,Hypersensitivity to any component of product.
Effects
Silver Nitrate produces potentially life-threatening effects which include Electrolyte and volume depletion, Methemoglobinemia. which are responsible for the discontinuation of Silver Nitrate therapy.The signs and symptoms that are produced after the acute overdosage of Silver Nitrate include Vomiting, Diarrhea, Convulsions, Coma, Shock, Metallic taste, Local trauma, Pain in mouth, Corneal opacification, Hemorrhagic gastroenteritis, Sialorrhea, Cataracts.The symptomatic adverse reactions produced by Silver Nitrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Conjunctivitis.
Indications
Silver Nitrate is primarily indicated in conditions like Bladder hemorrhage, Burn wounds, Eczema, Epidermal necrolysis, Haematuria, Hematuria, Interstitial cystitis, Nasal epistaxis, Ophthalmia neonatorum, Ophthalmia neonatorum, Pneumothorax, Rhinitis, Warts, and can also be given in adjunctive therapy as an alternative drug of choice in Aphthous and herpetic ulcers.
Interactions
Silver Nitrate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementSelenium (Sulphide)Sulfacetamide SodiumTopical sulfonamides are incompatible with silver salts.Concurrent use is not recommended.SulfisoxazoleSulphacetamide These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Protein-bound iodine estimation of Thyroid Function
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Pencil, Applicator Protect from Sunlight and Moisture.
Warnings
Do not use applicator sticks on the eyes. Prolonged use may result in skin discoloration.
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