Retinol (Vitamin A)

Retinol (Vitamin A) is a fat soluble vitamin and it was the first fat soluble vitamin discovered. Vitamin A is essential for normal visual function, for healthy skin and for growth. May consist retinol or its esters, formed from edible fatty acids, principally acetic acid and palmitic acid. The major source of viatmin A is yellow and green leafy vegetable and yellow fruits, egg yolk, liver, kidney and fish. Retinol (Vitamin A) is included in many multivitamin preparations.


Brands
DAYALETS OPTILETS-M PRAMET-FA PRAMET-FA VI-DAYLIN VI-DAYLIN VI-DAYLIN VISIONACE VIVIOPTAL SEVENSEAS COD LIVER SEVENSEAS COD LIVER SEVENSEAS COD LIVER ANGLOVIT THERAGRAN-H THERAGRAN-M CAMOVIT-L CAMOVIT-L CAMOVIT-M MINAMINO ONCE A DAY OCULUVIT OCULUVIT EXTRA VITAMIN A VITAMINOL MULTICAP-M ORACAP-T STARVIT PANVITAN-M VITRONEX MULTINA-33 MULTINA-33 HICAP-M HICAP-SS PREGNOVIT PEXOVIT PEXOVIT PEXOVIT SOVIT-M THERIN-M SUPER TINCHU VIT VITAVIT VITAVIT VITAVIT VITAVIT CURACAP-T UNIVIT UNIVIT-M MIOBI MULTIBIONTA MULTIBIONTA MULTIBIONTA MULTIBIONTA-M MULTINAF FERTIN VITALET-H VITALET-M ABDEC ABDEC POLYVIT POLYVIT-M UNICAP UNICAP-M UNICAP-T REVITON REVITON ROVIGON SUPRADYN-N AVITA GENATOSAN MINOLAD DYNAMIN-V DIADYNAM-G CALIX ZEEST VITAMIN-A GROVIT GROVIT CENTRUM MATERNA VI-MAGNA MVEM-21 MULTIMIN MULTIMIN MULTIMIN MULTIMIN VITONE ACE-BEX KARMAPLEX SEVENSEAS LIQ.ORANGE OPALEX MULTI OPALEX MULTI SEVENSEAS MVM SEVENSEAS MVM OPALEX EXTRA OPALEX EXTRA VI-CAPS DELMIN MAZIVIT M NUTRICAP-M VISAVIT GLOVIAN-E MULTONIC HONEYPLEX VIDAYLIN-M VIDAYLIN-M E-GEM SHAMPOO ADE E-GEM CREAM GENATOSAN PLUS IRON VIDAYLIN-L SUPRADYN XANTERVIT ONCE A DAY AX MULTIVITAMIN ACNE WASH ACNE WASH DIABETONE OPHTH-VIT A MULTITINE MULTITONE D-18 DREAM-18 ACNE PREGNATAL ENGRAN VADORAL VADORAL CODLI AD THERAPLEX QUANTUM GOLD QUANTUM SUPER NESLAC EPIVITE NEUROVIT-M WILGRAN-M Y-GOGIN M-BROVIT M-BROVIT VITAMIN A-POS VIDAYLIN-T MULTINA MAX MULTINA MAX MULTINA MAX MYVIT-T DIVASAS EUROVIT KIDS CAPROVIT WELMATON ACTIVAL XEROWET CORAMIN-G DERMOSOF ACNE ACTIVITAL FFERROPRO REMO MULTIVITAMIN MB-VITA THERIN VIT BABY ACTIVE GERIATRIC PHARMATON GERIATRIC PHARMATON CLOMVIT-F SEVENSEAS LIQ.CHERRY SEVENSEAS LIQ.PLAIN SEVENSEAS SEVENSEAS TAVIL ENGOR EVIVAL FITERNA REGNUM MYVIT-A
Adult Dose
Dose: 15000 to 500000 mg
Single Dose: 260000 (257500)
Frequency: 24 hourly
Route: PO
Instructions: As required
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose: 20000 IU/kg
Single Dose: 20000 (20000)
Frequency: As recommended.
Route: Oral
Instructions: For Once
Characteristics
Retinol (Vitamin A) also known as Antixeropthalmic Vitamin, Antixeropthalmic Vitamin, Antixeropthalmic Vitamin. . It is of Synthetic origin and belongs to Cyclohexane Nonatetraene. It belongs to Dermatological Products and Vitamin, Fat Soluble pharmacological group.The Molecular Weight of Retinol (Vitamin A) is 286.46.
Contraindications
Retinol (Vitamin A) is contraindicated in conditions like Hypersensitivity,Hypervitaminosis.
Effects
The severe or irreversible adverse effects of Retinol (Vitamin A), which give rise to further complications include Hair loss, Anorexia, Peeling & redness of skin.Retinol (Vitamin A) produces potentially life-threatening effects which include intracranial pressure. which are responsible for the discontinuation of Retinol (Vitamin A) therapy.The signs and symptoms that are produced after the acute overdosage of Retinol (Vitamin A) include redness o f skin.The symptomatic adverse reactions produced by Retinol (Vitamin A) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Irritability, Nausea, Vomiting, Hypersensitivity, Dry skin, Weight loss, Transient hydrocephalus, Hypercalcemia, Skin cracking, Hypervitaminosis.
Indications
Retinol (Vitamin A) is primarily indicated in conditions like Adjunctive therapy without valproate, Bronchitis, Pneumonia, Rsv infection, Skin diseases, To reduce degradation of pancreatic enzyme supplements, Vitamin deficiency, and can also be given in adjunctive therapy as an alternative drug of choice in Biliary cirrhosis, Cholestasis, Measles, Xerophthalmia.
Interactions
Retinol (Vitamin A) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAcitretinAlcoholBleomycinbleomycin decrease absorption of RetinolEtretinateIsotretinoinIsotretinoinMetacycline (HCl)Minocycline (HCl)NeomycinNeomycin decrease absorption of RetinolNeomycinParaffinTocopherol (Vitamin E)TretinoinWarfarin (Na)Vitamin A inhibit the metabolism of warfarin.ModerateAvoid intake of vitamin A during therapy. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 40°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Warnings
Supervise prolonged daily administration over 25000 IU. Evaluate Vit.A intake from diet, fortified food & drugs. Excessive dose of vitamin A should be avoided during pregnancy. Use with caution in patients with renal impairments, renal dialysis
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