NULCER NULCER ZENIT RANIDIN RANIDIN ULCENOR ZANTAC ZANTAC ZANTAC RENATIL RENATIL RANIMAX ANZOL ANZOL RANTIN RANTIN RANTIN PEPTAC PEPTAC PEPTAC LOMADRYL LOMADRYL RANULCID RANULCID RANULCID PEPTICURE CERTINE RANILOC RENATA RENATA RAMED-AC RAMED-AC RAKITAC RAKITAC RANCER-150 GLAMET RANAX RANAX RANAX DINETAC STOMACID STOMACID STOMACID PEPTINIL PEPTINIL PEPTINIL XETAC H2 REC H2 REC RENACID RANISON RANISON HEALALSER GERTOCALM HISTACID OBATIDINE RATAC RANITIDE ULSFREE RANISCOT RANISCOT RANISCOT MARIADIN RAMAT PUROD ULCEMED ULCEMED DUOTEC DUOTEC RENERA TATIDINE TEE-DIM RITADINE GEOTAC MARIQUINE RELIANCE RELIANCE RANITIDINE ULCER OFF RANEXIN RANEXIN SHALTAC ULTEC ULTEC RANTID RENATIL SUSP RENATIL SUSP HITAC RANIGARD OCTINA DEGUST RADICON REXOTIDE RESOTAC RA-NOT CHASE CHASE APSAR ACIDRAN NITID NITID NIPODUR NIPODUR FESNIDINE ALTAL ALTAL MONOCID MONOCID RATIDINE TABLET TIOBINE MACRIDINE NOULCE ACIDONIL RANIPEP RANIPEP NAZDAC QUNTIQUE RANISIFAR RANTAB ZANIATE RENEPH RENILOC BIODINE TABS NITIDINE ANINE DART DART RANSLY RATIDINE INJECTION DINOLIVE DINOLIVE NITISAF RANIMARK RINAI RINAI TAGNA ULCERID ULCERID DANITN FOZAB RANIZAN RIO ZOMTIC ACIGO DANITIN DEGAST KANTAC LAWRITIDINE NAZET RANI RANTAC RENOXID XETRON XETRON ZANIL ANATAC PYRAD PEPTIJECT

Dose: 150 mg
Single Dose: 150 (150)
Frequency: 8 hourly
Route: PO,IV,IM
Instructions:

Dose: 0.5 mg/kg
Single Dose: 0.5 (0.5)
Frequency: 6 hourly
Route: Intravenous
Instructions:

Dose: 0.5 to 1 mg/kg
Single Dose: 0.75 (0.75)
Frequency: 6 hourly
Route: Intramuscular
Instructions:

Ranitidine Bismutrex, Ranitidine Bismutrex, Ranitidine Bismutrex are the derivatives of Ranitidine. It is of Synthetic origin and belongs to Furanyl Amine. It belongs to H2-antagonist pharmacological group on the basis of mechanism of action and also classified in Histamine (H-2) Antagonists pharmacological group.The Molecular Weight of Ranitidine is 350.90. Its pKa is 2.3, 8.2.

Ranitidine is contraindicated in conditions like Hypersensitivity,Pregnancy,Porphyria,Breast feeding,Pain and inflammation (rheumatic disease).

The severe or irreversible adverse effects of Ranitidine, which give rise to further complications include Thrombocytopenia, Hepatitis, Hepatomegaly, Stevens johnson syndrome, Bradycardia, AV-block, Leucopenia, Acute pancreatitis, Pancytopenia, Marrow hypoplasia.The symptomatic adverse reactions produced by Ranitidine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Tiredness, Headache, Nausea, Diarrhea, Fever, Constipation, Rashes, Confusion, Erythema, Dysuria, Hallucination, Impotence, Darkening of stool and tongue, Depression, Arthralgia, Gynecomastia, Agitation, Anaphylactic shock.

'Ranitidine is primarily indicated in conditions like Benign gastric and duodenal ulceration, Benign gastric ulcer, Chronic episodic dyspepsia, Duodenal ulcer, Duodenal ulceration, Duodenal ulceration associated with H. Pylori, Gastric acid reduction (surgical procedures), Gastric acidity, Gastro-oesophageal reflux disease, Heart burn, Long-term treatment of healed gastro-oesophageal reflux disease, NSAID-associated ulceration, Peptic ulcer, Post-operative ulcer, Prophylaxis of acid aspiration in obstetric patients, Prophylaxis of NSAID-associated gastric or duodenal ulcer, Prophylaxis of NSAID-induced duodenal ulcer, Prophylaxis of NSAID-induced ulcer, Prophylaxis of recurrent haemorrhage, Prophylaxis of stress ulceration, Reflux oesophagitis, Zollinger-ellison syndrome, and can also be given in adjunctive therapy as an alternative drug of choice in Helicobacter pylori infection, Long-term treatment of healed reflux oesophagitis, Long-term treatment of reflux oesophagitis, Moderate to severe reflux oesophagitis, Prophylaxis of acid aspiration in obstetrics, Prophylaxis of mendelson''s syndrome, Surgical procedures.'

Ranitidine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlendronate (Na)Intravenous Radministration of Ranitidine was shown to double the bioavailablity of oral Alendronate (Na).Aluminium Hydroxide and OxideCeftibutenDabrafenibH2-receptor antagonists may alter the solubility of dabrafenib and reduce its bioavailabilityKetoconazoleRanitidine increases gastric pH and decrease the absorption of ketoconazole thus reduces its bioavailability upto 75% to 80% results decreased plasma level.ModerateCo-administration is not recommended.Metformin (HCl)Ranitidine reduces the excretion of metformin by competing for renal tubular transport results in increased level of metformin may lead to lactic acidosis.ModerateSlowly reduce the dose of metformin. Closely monitor the blood glucose level. Patient should notify to physician if experience signs of lactic acidosis.MidazolamNaproxenRanitidine increases the dissolution rate of enteric-coated naproxen so, drug release in stomach instead of small intestine.ModerateCombination should be avoidedin patient taking enteric-coated formulation.PramipexoleRanitidine decrease the clearance of pramipexole by ~20%.Sodium DiatrizoateShould not be use concurrently without informing doctor.SucralfateTolazoline (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Liver Function Test (LFT)

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Caps Store at room temperature, Below 25°C or in refrigerator. Do not Freeze. Protect from Sunlight and Moisture. Tab Store Below 40°C. Protect from Sunlight and Moisture.

Ranitidine should be used with caution in patients with impaired kidney or liver function. Intravenous injection should be given slowly and intravenous infusion is recommended in patients with cardiovascular impairment. Exclude the possibility of malignancy in gastric ulcer before instituting therapy. Regular supervision of patient with peptic ulcer and on non-steroidal anti-inflammatory drugs is recommended, especially if eldery.Should be avoided in the patient with history of acute porphyria.Ranitidine Bismuth Citrate should be used with caution in hepatic impairment, in renal impairment, pregnancy, breast feeding.H2 receptor antagonists might mask the symptoms of gastric cancer; perticular care is required in those whose symptoms change and in those who are middle-aged or over.