AFRAZID AFRAZID-P RIFADOS RIMATOL-P PYRAZINAMIDE PYRAZINAMIDE PYRAZINAMIDE PZA CIBA 500 PZA CIBA 500 RIFIN RIFIN-P RIFIN-P PYRAZIN PYRAZIN RISOMIDE RISOMIDE ERI-P PIRAMIDE PIRAMIDE PYRATAR MYRIN-P PYRAZINAMIDE PYRAZINAMIDE PYRAZINAMIDE PYRAZINAMIDE TUBERIN-P PYRAZID PYRAZID RIFAZOL PEDIATRIC MYRAZID-P RIFATER TBRID ZINAMID RIFA 4 PLUS RIFAZOL+ PYRAGEN PYRAGEN ERI-PLUS RIFINZID-4 RIFINZID FORTE MYRIN-P FORTE MEDIZINAMIDE MEDIZINAMIDE TIBEX-P RIFIN FORTE RIMSTAR RIFEDOT-4 RIMCURE ASKAMIDE ASKAMIDE ZINATAB ACORET-P TEEBAZID ERI-P FORTE RIFA 4 UBUTOL+3 UBUTOL+3 PYRAKIM PYRAKIM PYRAZINAMIDE CYREX-P RIPE ATD+2 ATD+3 ATD+4 ETHRIFID P PYZAM TUBERCURE-P MYCORID P ROMIZID RISEN P PRIMACID PYRAMIDE TUBERWIN-P FORTE AMANTE-PF PIRE PIRE-P RIMATOL FORTE P RIMKID

Dose: 20 to 35 mg/ kg
Single Dose: 28 (27.5)
Frequency: As recommended.
Route: PO
Instructions: Daily in 3-4 div.doses. Maximum dose: 3 g/24hr. Usually given during 1st 2 months of therapy.

Dose: 5 mg/kg
Single Dose: 5 (5)
Frequency: 6 hourly
Route: Oral
Instructions:

Dose: 5 mg/kg
Single Dose: 5 (5)
Frequency: 6 hourly
Route: Oral
Instructions: For Paeds of All Ages

. It is of Synthetic origin and belongs to Amidopyrazine. It belongs to Antimycobacterial agent pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group.The Molecular Weight of Pyrazinamide is 123.10. Its pKa is 0.5.

Pyrazinamide is contraindicated in conditions like Renal diseases,Hepatic disease.

The severe or irreversible adverse effects of Pyrazinamide, which give rise to further complications include Sideroblastic anemia, Precipitation of gout.Pyrazinamide produces potentially life-threatening effects which include Hepatitis, Hyperbilirubinemia. which are responsible for the discontinuation of Pyrazinamide therapy.The symptomatic adverse reactions produced by Pyrazinamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anorexia, Fever, Malaise, Arthralgia, Nausea and vomiting.

Pyrazinamide is primarily indicated in conditions like Acute leukemia, Tuberculosis (with other anti-tuberculosis drugs), and can also be given in adjunctive therapy as an alternative drug of choice in Tuberculosis.

Pyrazinamide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementIsoniazidProbenecidSulphinpyrazoneZidovudine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Acetest Ketostix qualitative urine test for Ketones

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Moisture and Heat.

Pyrazinamide should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with any pre-existing kidney disease, liver disease, gout, diabetes or if have any allergy.