Propyliodone

Propyliodone used as radiopque medium for brochographic use. When directly instilled into the bronchi resulting in well-defined bronchograms for atleast 30 min. Because of its toxicity, Propyliodone should only be used if absolutely essential.


Brands
Adult Dose
Dose: 128.57 to 171.43 mg/kg
Single Dose: 150 (150)
Frequency: As recommended.
Route: Inhalation
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Iodinated Radio-opaque Compounds. It belongs to Radiopaque Agents pharmacological group on the basis of mechanism of action and also classified in Diagnostic Aids pharmacological group.The Molecular Weight of Propyliodone is 447.00.
Contraindications
Propyliodone is contraindicated in conditions like Asthma,Bronchospasm,Infections,Obstructive airway disease,Heart disease.
Effects
The severe or irreversible adverse effects of Propyliodone, which give rise to further complications include Fever, Bleeding, Hematoma, Dysphagia, Laryngeal perichondritis.Propyliodone produces potentially life-threatening effects which include Fever, Anaphylaxis, Repiratory obstruction, Cerebral embolization. which are responsible for the discontinuation of Propyliodone therapy.The signs and symptoms that are produced after the acute overdosage of Propyliodone include Airway obstruction.The symptomatic adverse reactions produced by Propyliodone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fever, Malaise, Nausea and vomiting, Aching joints.
Indications
'Propyliodone is primarily indicated in conditions like Paget''s disease of bone, Radiological contrast agent.'
Interactions
No data regarding the interactions of Propyliodone was found.
Interfrence
Thyroid Function Test based on iodine measurements Respiratory Function Test
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store in a well closed container. Protect from Sunlight.
Warnings
Propylidone should be used with caution in patients with history of hypersensitivity to iodine. Avoid use in patients with heart disease. It should be used with caution in patients with asthma, pulmonary emphysema. It should be used with extreme caution during pregnancy.
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