Dose: 10 to 40 mg/kg
Single Dose: 25 (25)
Frequency: 8 hourly
Route: PO
Instructions: -

Dose: 20 to 25 mg/kg
Single Dose: 22 (22.5)
Frequency: 8 hourly
Route: Oral
Instructions: -

. It is of Synthetic origin and belongs to Isoquinolones. It belongs to Anthelmintics pharmacological group.The Molecular Weight of Praziquantel is 312.40. Its pKa is > 3.

Praziquantel is contraindicated in conditions like Ocular cysticercosis.

The severe or irreversible adverse effects of Praziquantel, which give rise to further complications include Abdominal pain, Jaundice.The symptomatic adverse reactions produced by Praziquantel are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Dizziness, Fever, Skin reactions.

Praziquantel is primarily indicated in conditions like Fluke infections, Helminth infection, Schistosomiasis.

Praziquantel is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlbendazoleAlcoholCarbamazepineChloroquineCimetidine (HCl)FosphenytoinPhenytoin (Na)VORICONAZOLEVoriconazole may increase the serum concentration of praziquantel by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects . These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Haemoglobinopathies Tests G6PD Tests

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 30°C.

Patients should be observed caution while driving or performing other tasks requiring alertness, because it may produced drowsiness or dizziness. Avoid use of praziquantel during lactation.