VERSTRAN

Dose: 30 mg
Single Dose: 30 (30)
Frequency: 24 hourly
Route: PO
Instructions: At bed time

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Synthetic origin and belongs to Benzodiazepine. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Benzodiazepine pharmacological group.The Molecular Weight of Prazepam is 324.80. Its pKa is 2.7.

Prazepam is contraindicated in conditions like Psychosis,Pulmonary insufficiency,Respiratory depression,Phobias.

The severe or irreversible adverse effects of Prazepam, which give rise to further complications include Diarrhoea, Confusion, Insomnia, Irritability, Psychosis, Depression, Sweating, Nervousness.The signs and symptoms that are produced after the acute overdosage of Prazepam include Unconsciousness, Respiratory depression, Ataxia, Dizziness, Slurred speech.The symptomatic adverse reactions produced by Prazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Excitement, Ataxia, Blurred vision, Confusion, Sedation, Psychotic symptoms, Paradoxical effects, Aggression.

Prazepam is primarily indicated in conditions like Alcohol withdrawal, Anxiety, Insomnia, Muscular spasm.

Prazepam is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAtropine (Sulphate)Cimetidine (HCl)DisulfiramMetoclopramide (HCl)MorphinePethidine (HCl)VORICONAZOLEVoriconazole may increase the serum concentration of prazepam by decreasing its metabolism. Monitor for prazepam toxicity These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Caps Store Below 40°C. Protect from Sunlight and Moisture.

Perform periodic blood counts and liver function tests during long term therapy. Prazepam should be used with caution in patients if increased salivation cause respiratory difficulty, because it may produce an increase in salivation. Give least amount of drug to patients in whom depression accompanies anxiety and suicidal tendencies may be present. It should be used with caution (if it contains tartrazine)in patients with aspirin hypersensitivity because it may cause allergic reaction (including bronchial asthma).