Potassium Permanganate

Potassium Permanganate is a strong oxidizing agent exerts its antibacterial and antifungal propertieaction against organism susceptible to nascent oxygen. Potassium Permanganate is used for bladder irrigation, urethritis. Potassium Permanganate is used as an astringent in conditions like eczema dermatitis and ivy poisoning. Potassium Permanganate is also capable of oxidizing certain drugs and venoms. In the treatment of poisoning following oral ingestion of barbiturates, chloral hydrate and many alkaloids, gastric levage with a solution of potasium permanganate helps to destroy the poison and thus prevent absorption.

Brands
MAGENTA
Adult Dose
Dose: 0.03 to 0.1 %
Single Dose: 0.065 (0.065)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Neonatal
Dose: 0.03 to 0.1 %
Single Dose: 0.065 (0.065)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Paedriatic
Dose: 0.03 to 0.1 %
Single Dose: 0.065 (0.065)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Characteristics
. It is of Synthetic origin and belongs to Oxidizing Agent. It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action and also classified in Dermatological Products pharmacological group.The Molecular Weight of Potassium Permanganate is 158.00.
Contraindications
Potassium Permanganate is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Potassium Permanganate, which give rise to further complications include Ulceration, Corrosive burns.Potassium Permanganate produces potentially life-threatening effects which include Nausea, Vomiting, Cyanosis, Methemoglobinemia, GI ulceration, Oral ulceration, Metabolic acidosis. which are responsible for the discontinuation of Potassium Permanganate therapy.The signs and symptoms that are produced after the acute overdosage of Potassium Permanganate include Acidosis, Cardiopulmonary arrest, Methemoglobinemia, Hypermangnesemia, Corrosive pleurisy, Pericarditis.
Indications
Potassium Permanganate is primarily indicated in conditions like Bromhidrosis, Dermatophytic infections, Fungal infection, Hyperhidrosis, and can also be given in adjunctive therapy as an alternative drug of choice in Hypopigmentation, Infected genital lesion, Infected oral lesion.
Interactions
No data regarding the interactions of Potassium Permanganate was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container.
Warnings
Administer potassium products with caution to hypokalemic hypertensive patients, because it will lower the blood pressure.
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