Poldine (Methylsulphate)

Poldine (Methylsulphate) reduces acid secretion of stomach and is used in the treatment of peptic ulcer.


Brands
Adult Dose
Dose: 0.171 to 0.714 mg/kg
Single Dose: 0.44 (0.4425)
Frequency: 24 hourly
Route: PO
Instructions: -
Neonatal
Dose: Not used in this age group
Single Dose:
Frequency:
Route:
Instructions:
Paedriatic
Dose: 0.2 mg/kg
Single Dose: 0.2 (0.2)
Frequency: 24 hourly
Route: Oral
Instructions: At bed time
Characteristics
. It is of Synthetic origin and belongs to Pyrole. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Gastrointestinal Anticholinergics/Antispasmodics pharmacological group.The Molecular Weight of Poldine (Methylsulphate) is 451.50.
Contraindications
Poldine (Methylsulphate) is contraindicated in conditions like Cardiac arrhythmia,Mania,Myocardial infarction,Heart block,Narrow-angle glaucoma,Hypersensitivity,Urinary retention.
Effects
The signs and symptoms that are produced after the acute overdosage of Poldine (Methylsulphate) include Tachycardia, Confusion, Hallucinations, Delirium, Tachypnea, Hyperpyrexia, Excitation.The symptomatic adverse reactions produced by Poldine (Methylsulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tachycardia, Constipation, Dry mouth, Blurred vision, Urinary hesitancy.
Indications
Poldine (Methylsulphate) is primarily indicated in conditions like Cataplexy, Depression, Obsessive-compulsive disorders, Peptic ulcer, Phobic states, and can also be given in adjunctive therapy as an alternative drug of choice in Acne, Endocrine adenomas, Hyperhidrosis, Zollinger-ellison syndrome.
Interactions
No data regarding the interactions of Poldine (Methylsulphate) was found.
Interfrence
Risks
Drug should not be given to Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab
Warnings
No data regarding the Warnings/Precuations of Poldine (Methylsulphate) is available.
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